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Rosuvastatin Calcium CAS: 147098-20-2 Soo saaraha
Kaalshiyamka Rosuvastatin waa horjooge tartan u ah hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, enzyme-ka kicinaya beddelka HMG-CoA oo loo beddelo mevalonic acid, tallaabada xaddidaysa heerka kolestaroolka biosynthesis.Kaalshiyamka Rosuvastatin waa antilipemic waxaana loo isticmaalaa in lagu yareeyo heerarka kolestaroolka plasma iyo ka hortagga cudurrada wadnaha iyo xididdada dhiigga.
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Glycine CAS: 56-40-6 Soo saaraha soo saaraha
Glycine waa qaabka ugu fudud ee 20ka xubnood ee taxanaha amino acid, oo sidoo kale loo yaqaano amino acetate.Waa amino acid aan muhiim u ahayn jidhka bini'aadamka waxayna ka kooban tahay labadaba aashitada iyo kooxda shaqada aasaasiga ah ee gudaha molecule-keeda.Waxay soo bandhigaysaa sida elektrolyte xoog leh xal aqueous ah, oo waxay leedahay milmay weyn ee dareerayaasha polar xooggan laakiin ku dhawaad aan milmin in dareerayaasha non-polar.Intaa waxaa dheer, waxa ay sidoo kale leedahay qaraabo dhibic dhalaalaysa sare iyo barta karkaraya.Hagaajinta pH ee xalka aqueous wuxuu ka dhigi karaa glycine inuu muujiyo qaabab kala duwan oo kelli ah.
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L-Arginine Pyroglutamate CAS: 56265-06-6 Soo saaraha
L-Arginine pyroglutamate, oo sidoo kale loo yaqaan pirglutargine iyo arginine pidolate, waa L-arginine cusbada pyroglutamic acid.Arginine pyroglutamate waa qaab keenista arginine.L-Arginine-L-pyroglutamate waxaa sida caadiga ah loo isticmaalaa dhexdhexaadinta dawooyinka.
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Dapagliflozin Propanediol CAS: 461432-26-8
Dapagliflozin Propanediol, Sodium glucose cotransporter 2 inhibitor, waa nooc cusub oo ah dawada ka hortagga sonkorowga;Waxa loo isticmaali karaa door muhiim ah daawaynta maandooriyaha ee sonkorowga, waxaana loo isticmaali karaa cunto caawiye ah iyo jimicsi si loo hagaajiyo xakamaynta sonkorta dhiigga ee dadka waaweyn ee qaba nooca 2aad ee sonkorowga.
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Leflunomide CAS: 75706-12-6 Soo saaraha Soo saaraha
Leflunomide waa daawo afka laga heli karo oo wax ka beddeleysa cudur-ka-hortagga xanuunka waxaana loo bilaabay sidii Arava gudaha Mareykanka si loogu daweeyo rheumatoid arthritis-ka (RA);waa daawada kaliya ee ugu horeysa oo la tilmaamo si loo yareeyo burburka wadajirka ah ee RA, sidaas darteed wax ka qabashada baahida caafimaad ee aan la daboolin. Leflunomide waa dawo-yaqaan oo si degdeg ah oo gebi ahaanba u metabolized (nolosha nus, <60 daqiiqo) ka dib afka. maamulka teriflunomide, farmashiyoolaji firfircoon α-cyanoenol metabolite.
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Tofacitinib CAS: 477600-75-2 Soo saaraha
Tofacitinib waa kii ugu horreeyay ee kinase inhibitor yar oo loo oggolaaday daawaynta RA.Tofacitinib waa horjooge ka mid ah afarta nooc ee Janus kinase (JAK): JAK1, JAK2, JAK3, iyo Tyk2.Tofacitinib waxay u dhaqmaan iyadoo la xakameynayo fosforyaalka iyo kicinta transducers signals iyo activators of transcription (STATs), taas oo xakameynaysa soo saarista dhexdhexaadiyeyaasha bararka. unugyada wadajirka ah.
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Aspartic Acid CAS: 56-84-8 Soo saaraha Soo saaraha
Aspartic acidwaxaa loo isticmaalaa kabitaan cunto ahaan, waxaa lagu qasi karaa macdan si loo sameeyo xeryahooda sida potassium aspartate, copper aspartate, manganese aspartate, magnesium aspartate, zinc aspartate iyo kuwo kale.Kordhinta nuugista, iyo ka faa'iidaysiga awoodaha, macdantan iyada oo lagu daro aspartate waxay keenaysaa faa'iidooyin caafimaad oo gaar ah.Ciyaartoyda badan ayaa isticmaala kabka macdanta L-aspartic acid afka si ay u xoojiyaan awoodooda waxqabad.Aspartic acid iyo glutamic acid waxay ciyaaraan door muhiim ah sida asiidhyada guud ee xarumaha firfircoon ee enzyme, iyo sidoo kale ilaalinta milanka iyo dabeecada ionic ee borotiinnada.
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Cetilistat CAS: 282526-98-1 Soo saaraha Soo saaraha
Cetilistat waa nooc cusub oo pancrelipase inhibitor ah oo loogu talagalay daawaynta buurnaanta ee bukaanka macaanka iyo kuwa aan sonkorowga lahayn, wax-qabad dheer oo awood leh oo gaar ah lipase inhibitor caloosha, kaas oo ka ciyaara saameyn daweyn ah iyada oo la samaynayo bond covalent leh goobta firfircoon ee serine ee lipase gastric lipase. iyo lipase pancreatic ee caloosha iyo mindhicirka yar si ay u dhaqaajiso enzyme.Enzymes-ka Buuga Kiimikada Nolosha ma hydrolysayn karaan dufanka cuntada, badiyaa triglycerides oo gala asiidh dufan ah oo bilaash ah iyo monoacylglycerols.Triglycerides-ka aan dheefshiidka lahayn jidhku ma nuugi karo, taas oo hoos u dhigaysa qaadashada kalooriga iyo xakamaynta miisaanka.
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Paroxetine HCL CAS: 78246-49-8 Soo saaraha
Paroxetine hydrochloride waa cusbada hydrochloride ee paroxetine.Waa daawo liddi ku ah niyad-jabka.Waxay leedahay door sida antidepressant, daroogada anxiolytic, wakiilka hepatotoxic, P450 inhibitor ah iyo serotonin kor u qaadida inhibitor.Waxay ka kooban tahay paroxetinium (1+).
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Famotidine CAS: 76824-35-6
Famotidine waa histamine H2-receptor antagonist, kaas oo kor u qaada bogsashada hunguriga erosive, boogaha gastric iyo duodenal tan iyo markii ay joojiso dheecaanka acid gastric ee bini'aadamka.It waxaa loo isticmaalaa daawaynta iyo ka hortagga boogaha ku dhaca caloosha iyo xiidmaha.Waxa kale oo ay daweyn kartaa cudurrada ay ka mid yihiin Zollinger-Ellison syndrome oo calooshu ku ururto xaddi xad-dhaaf ah oo asiidh ah.Waxaa intaa dheer, waxaa sidoo kale lagu dabaqaa inta lagu jiro daawaynta cudurka reflux gastroesophageal (GERD) iyo xaaladaha hypersecretory pathological.
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Rivaroxaban CAS: 366789-02-8 Soo saaraha
Rivaroxaban waa wakiilka cusub ee antithrombotic.Waa sheeko cusub, afka ah, horjooge toos ah oo la xushay ee factor Xa oo ay samaysay Bayer Healthcare.Waxay u ansixiyeen EMEA iyo FDA ka hortagga xinjirowga xididdada dhiigga ee bukaannada qaangaarka ah ka dib wadarta beddelka miskaha ama wadarta qalliinka beddelka jilibka.
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Glutamine CAS: 56-85-9 Soo saaraha Soo saaraha
Glutamine waa alfa-amino acid oo ka mid ah 20-ka amino acid ee ka kooban borotiinno.L-glutamine waa asiidhyada amino-ka ee aan daruuriga ahayn sidoo kale waa amino acids-ka ugu badan ee jidhka bini'aadamka.Waxay ku lug leedahay habab badan oo bayooloji oo muhiim ah.Tusaale ahaan, waxa ay dhisme u tahay isku-xidhka borotiinka oo ah hal amino acid oo muhiim ah;waxaa loo isticmaalaa biosynthesis ee urea iyo purines loogu talagalay isku dhafka acid nucleic;waa substrate u ah biosynthesis ee neurotransmitters;sidoo kale waa ilo muhiim ah oo laga helo tamarta gacanta.
