Leflunomide CAS:75706-12-6 Alaab-qeybiye Soo-saare

Leflunomide waa daawo afka laga qaato oo wax ka beddesha cudurrada, waxaana laga bilaabay Arava gudaha Mareykanka si loogu daaweeyo rheumatoid arthritis (RA); waa daawada ugu horreysa uguna keliya ee la tilmaamay inay hoos u dhigto dhaawaca wadajirka ah ee RA, sidaas darteed wax ka qabashada baahida caafimaad ee aan la dabooli karin. Leflunomide waa daawo ka hortagta oo si dhakhso ah oo gebi ahaanba la dheefshiido (nus-nololeed, <60 daqiiqo) ka dib marka afka laga qaato teriflunomide, oo ah metabolite-ka α-cyanoenol ee firfircoon ee dawooyinka.

Dalbo ama Codso Qiimayn

Faahfaahinta Badeecada

Calaamadaha Alaabta

Codsiga iyo Saamaynta

Leflunomide ma firfircoona, laakiin teriflunomide waxay joojisaa isku-darka pyrimidine de novo qiyaaso daaweyn oo hooseeya iyadoo joojinaysa dihydrorotate dehydrogenase (enzyme-ka go'aamiya heerka ee isku-darka UMP), yareynta isku-darka DNA-da iyo RNA, iyo joojinta wareegga taranka unugyada iyo soo saarista unugyada difaaca jirka. Yaraynta dihydrorotate ilaa orotate waxay dhacdaa isla marka la yareeyo cofactor-keeda, ubiquinone (coenzyme Q). Joojinta dihydrorootate dehydrogenase ee teriflunomide waxay muujinaysaa kinetics aan tartan lahayn oo aan tartan lahayn. Maamulka leflunomide ee bukaanada qaba rheumatoid arthritis waxay keentaa ka saarista sii socota ee unugyada B iyo hoos u dhigista habka difaaca jirka.

Muunadda Badeecada

Baakaynta Alaabta:

Macluumaad Dheeraad ah:

Halabuurka	C12H9F3N2O2
Baaritaan	99%
Muuqaalka	Budada cad
Lambarka CAS.	75706-12-6
Baakad	25KG
Muddada Khafiska	2 sano
Kaydinta	Ku kaydi meel qabow oo qalalan
Shahaadada	ISO.