Rosuvastatin Calcium CAS:147098-20-2 Bixiyaha Soo-saaraha

Kaalshiyamka Rosuvastatin waa daawo door ah oo ka hortagta HMG-CoA reductase. HMG-CoA reductase inhibitor waa enzyme-ka xaddidaya heerka hydroxy-3-methylglutaryl coenzyme A ee kala-guurka ah si uu u noqdo valerate A (horumariyaha kolestaroolka). Goobta ugu weyn ee uu ka shaqeeyo rosuvastatin waa beerka - xubnaha bartilmaameedka u ah yaraynta kolestaroolka. Rosuvastatin wuxuu kordhiyaa tirada soo-dhoweeyayaasha LDL ee beerka ee dusha sare ee unugyada, isagoo kor u qaadaya nuugista iyo catabolism-ka LDL, wuxuu joojiyaa isku-darka beerka ee VLDL, taasoo yareynaysa tirada guud ee walxaha VLDL iyo LDL. Kaalshiyamka Rosuvastatin wuxuu awood u leeyahay inuu si tartan ah u joojiyo beerka methylglutaryl coenzyme A reductase, wuxuuna sii wadaa saameyntiisa wanaagsan ee yareynta dufanka. Waxay leedahay cimri dheer. Jinsiga iyo da'da bukaanada saameyn weyn kuma lahan dheef-shiid kiimikaadka daawooyinka.