Sodium Alpha-Ketoisocaproate CAS:4502-00-5 Alaab-qeybiye Soo-saare

Sodium Alpha-Ketoisocaproate waa metabolite leucine ah oo loo yaqaan inuu kiciyo dheecaanka insulin-ta ee ka yimaada unugyada β ee ganaca. Faleebo gudaha ah oo ah aα-Ketoisocaproate ayaa la ogaaday inay yareyso xaaladda endotoxemic. Jidhyada ketone ee ka dhasha beddelka, waxay u adeegi karaan sidii ilo tamar. Uruurinta α-Ketoisocaproic acid waxaa lagu gartaa ketoaciduria silsilad laamood ah, taas oo ay ugu wacan tahay la'aanta dhaqdhaqaaqa dehydrogenase ee acid L-2-keto. α-Ketoisocaproic acid waxay sababtaa kala go'a falgalka fosfooraska oksaydhka waxayna u dhaqantaa sidii ka hortag dheef-shiid kiimikaadka ee α-ketoglutarate dehydrogenase. Sidaas darteed, waxay horseeddaa cillad ku timaadda homeostasis-ka mitochondrial, oo lagu arkay silsilad laamood ah ketoaciduria.