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Lasmiditant CAS:439239-90-4
Lasmiditan, oo lagu suuq geeyo magaca Reyvow, waa isku-darka dawooyinka cusub ee loogu talagalay in lagu yareeyo weerarrada madax-xanuunka daran ee dadka waaweyn. Waxay ka tirsan tahay fasalka agonist-ka serotonin-ka ee xulashada ah, gaar ahaan kuwa bartilmaameedsada nooca hoose ee receptor-ka 5-HT1F. Habkan ficilku wuxuu Lasmiditan ka soocaa daaweynta madax-xanuunka ee dhaqameed, maadaama uusan kicinayn xididdada dhiigga, taasoo ka dhigaysa mid ku habboon bukaanada qaba arrimaha khatarta wadnaha iyo xididdada dhiigga.
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N-Methylcarbonyl-2-chloroacetamidrazone CAS:155742-64-6
N-Methylcarbonyl-2-chloroacetamidrazone waa isku-dhis kiimiko ah oo loo yaqaan codsiyadeeda kala duwan ee isku-darka dabiiciga ah iyo kiimikada isku-dubaridka. Isku-darka waxa ku jira falgalka N-methylcarbamoyl chloride oo leh 2-chloroacetohydrazide, taasoo keentay isku-dhis leh sifooyin qaab-dhismeed iyo shaqo oo kala duwan. Isku-darkani waxa lagu gartaa awoodda uu u leeyahay inuu sameeyo isku-dhisyo leh ion bir ah oo kala duwan, taasoo ka dhigaysa mid qiimo leh daraasadaha isku-dubaridka kiimikada. Intaa waxaa dheer, kooxaheeda carbonyl iyo amidrazone waxay gacan ka geystaan fal-celintooda iyo hawlahooda dawooyinka ee suurtagalka ah, kuwaas oo ah meelaha xiisaha cilmi-baarista socda.
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Lasmiditan HCl CAS:613677-28-4
Lasmiditan hydrochloride (Lasmiditan HCl) waa maaddo daawooyin ah oo caan ku ah doorka ay ka qaadato daaweynta weerarrada madax-xanuunka daran ee dadka waaweyn. Lasmiditan HCl wuxuu u soo baxay sidii agonist serotonin receptor ah oo la xushay, gaar ahaan bartilmaameedsanaya nooca hoose ee receptor-ka 5-HT1F, wuxuuna u taagan yahay horumar la taaban karo oo ku saabsan daaweynta madax-xanuunka sababtoo ah farsamo gaar ah oo ficil ah iyo waxtarkeeda caafimaad.
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(6-aMinopyridin-2-yl)(1-Methylpiperidin-4-yl)Methanone CAS:613678-03-8
(6-Aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone, oo sidoo kale loo yaqaan aminopyridine methylpiperidone, waa isku-dhis kiimiko ah oo saameyn weyn ku leh kiimikada daawada iyo cilmi-baarista dawooyinka. Iyada oo lagu soo saaray falgalka 6-aminopicolinic acid oo leh 1-methylpiperidin-4-one, isku-darkani wuxuu muujiyaa astaamo qaab-dhismeed oo gaar ah oo gacan ka geysta awooddiisa daawada iyo kala-duwanaanshaha shaqada.
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(S)-(+)-3-Quinuclidinol CAS:34583-34-1
(S)-(+)-3-Quinuclidinol, oo sidoo kale loo yaqaan quinuclidinol, waa isku-dhis muhiim ah oo ku jira kiimikada dabiiciga ah iyo cilmi-baarista dawooyinka sababtoo ah gaar ahaanshaheeda qaab-dhismeedka iyo codsiyada kala duwan. Isku-darka chiral-ka waxaa laga soo qaatay quinuclidine wuxuuna muujiyaa sifooyin kiimiko iyo daawo oo kala duwan oo soo jiitay dareenka qaybaha kala duwan ee sayniska.
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DHAMMAADAHA KHALADKA AH CAS:171482-05-6
Daawooyinka dhexdhexaadka ah ee loo yaqaan 'Aprepitant' waxay door muhiim ah ka ciyaaraan isku-darka daawada ee aprepitant, oo ah daawada neurokinin-1 (NK1) ee awoodda badan ee loo isticmaalo ka hortagga lallabbo iyo matag ay keento kiimoterabiga (CINV). Daawooyinkan dhexdhexaadka ah waa qaybo muhiim ah oo ka mid ah dariiqa isku-dhafka ah ee dhowr tallaabo ah oo horseedaya qaab-dhismeedka kama dambaysta ah ee aprepitant. Aprepitant lafteeda waxaa loo aqoonsan yahay waxtarkeeda maaraynta CINV, iyadoo siinaysa gargaar weyn bukaanada qaadanaya kiimoterabiga. Isku-darka aprepitant wuxuu ku lug leeyahay dhowr tallaabo oo muhiim ah, iyadoo dhexdhexaadiyayaashu ay u adeegaan sidii baloogyo dhisme oo awood u siinaya soo saarista hufan ee wakiilkan daaweynta ee muhiimka ah.
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2,4,6-TRIFLUOROBENZOYL CHLORIDE CAS:79538-29-7
2,4,6-Trifluorobenzoyl chloride, oo sidoo kale loo yaqaan trifluorobenzoyl chloride, waa isku-dhis kiimiko oo muhiim ah oo lagu qiimeeyo adeegsigeeda kala duwan ee isku-darka dabiiciga ah iyo hababka warshadaha. Iyada oo lagu sameeyay koloriin ku darista 2,4,6-trifluorobenzoic acid, isku-darkani wuxuu muujiyaa sifooyin kiimiko oo gaar ah oo gacan ka geysta isticmaalkiisa baahsan ee qaybaha kala duwan.
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4-Chloro-6-iodoquinazoline CAS:98556-31-1
4-Chloro-6-iodoquinazoline waa isku-dhis kiimiko ah oo leh qaacidada molecular-ka C9H5ClIN2. Waxaa lagu gartaa joogitaanka atamka chlorine iyo iodine ee ku xiran qaab-dhismeedka giraanta quinazoline. Isku-darkaan waxaa inta badan loo isticmaalaa cilmi-baarista dawooyinka iyo isku-darka dabiiciga ah sababtoo ah codsiyada suurtagalka ah ee horumarinta daawooyinka cusub iyo molecules kale oo firfircoon oo bayooloji ah.
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(R)-3-Quinuclinol CAS:25333-42-0
(R)-3-Quinuclinol, oo sidoo kale loo yaqaan quinuclidinol, waa isku-dhis muhiim ah oo ku jira kiimikada dabiiciga ah iyo cilmi-baarista dawooyinka sababtoo ah gaar ahaanshaheeda qaab-dhismeedka iyo codsiyada kala duwan. Isku-darka chiral-kan waxaa laga soo qaatay quinuclidine wuxuuna muujiyaa sifooyin kiimiko iyo daawo oo kala duwan oo soo jiitay dareenka qaybaha kala duwan ee sayniska.
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![(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT235.png)
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5
Isku-darka (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate waa molecule dabiici ah oo isku dhafan oo leh astaamo gaar ah oo qaab-dhismeed iyo daawooyin ah. Waxay ka tirsan tahay fasalka morpholine ee isku-dhafka, kuwaas oo inta badan loo isticmaalo kiimikada daawada sababtoo ah hawlahooda kala duwan ee bayoolojiga.
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![(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzemethanamine CAS:608141-42-0](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG304.png)
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzemethanamine CAS:608141-42-0
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzemethanamine waa isku-dhis kiimiko ah oo loo aqoonsaday adeegsigeeda kala duwan ee isku-darka dabiiciga ah iyo kiimikada daawada. Iyada oo lagu sameeyay falgalka (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone oo leh ammonia ama amine, isku-darkani wuxuu leeyahay astaamo qaab-dhismeed oo gaar ah oo gacan ka geysta kala duwanaanshaha shaqadiisa iyo hawlo daawo oo suurtagal ah.
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(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine CAS:608142-27-4
(R)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine waa isku-dhis kiimiko ah oo loo yaqaan adeegsigeeda kala duwan ee isku-darka dabiiciga ah iyo kiimikada daawada. Iyada oo lagu sameeyay falgalka 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone oo leh ammonia ama amine, isku-darkani wuxuu muujiyaa astaamo qaab-dhismeed oo gaar ah oo gacan ka geysta kala-duwanaanshihiisa shaqo iyo hawlo daawo oo suurtagal ah.
