Fiitamiin B13 (Asiidh Orotic ah) CAS: 65-86-1 Alaab-qeybiye Soo-saare

Aashitada Orotic (oo sidoo kale loo yaqaan pyrimidinecarboxylic acid) waa aashitada heterocyclic; waxaa sidoo kale loo yaqaan. Taariikh ahaan waxaa la aaminsanaa inay qayb ka tahay isku-dhafka fitamiin B waxaana loo yaqaanay fiitamiin B13, laakiin hadda waa la ogyahay inaysan ahayn fiitamiin. Waxaa si fiican loogu yaqaanaa horudhaca biosynthesis-ka pyrimidines; naasleyda waxaa laga sii daayaa mitochondrial dihydrorotate dehydrogenase (DHODH) si loogu beddelo UMP iyadoo la adeegsanayo enzyme-ka UMP synthase ee cytoplasmic. OA sidoo kale waa qayb caadi ah oo ka mid ah cuntada, iyadoo laga helo caanaha iyo waxyaabaha caanaha laga sameeyo, waxaana loo beddelaa uridine si loogu isticmaalo marinnada badbaadinta pyrimidine inta badan beerka, kelyaha iyo unugyada dhiigga cas.

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Codsiga iyo Saamaynta

Aashitada Orotic waa dhexdhexaad ku jirta biosynthesis-ka de novo pyrimidine kaas oo loo isticmaali karo in lagu barto gaar ahaanshaha iyo kinetics-ka orotate phosphoribosyltransferase (OPRT) kaas oo kiciya wareejinta phosphoribosyl ee la rogi karo laga bilaabo 5?-phospho-α-d-ribose 1?-diphosphate (PRPP) una gudubta aashitada orotic (OA), iyadoo sameysa pyrophosphate iyo orotidine 5?-monophosphate (OMP). Waxaa loo isticmaalaa sidii agab bilow ah oo loogu talagalay wax soo saarka ganacsi ee suurtagalka ah ee uridine 5?-monophosphate (UMP) oo ay sameeyaan microbes sida Corynebacterium ammoniagenes (ATCC 6872) ama Saccharomyces cerevisiae. Waxaa loo isticmaali karaa in lagu barto wadada calaamadaynta unugyada ku tiirsan AMPK/SREBP-1 iyo hababka nidaaminta qoraalka ee kiciya lipogenesis-ka beerka.

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Baakaynta Alaabta:

Macluumaad Dheeraad ah:

Halabuurka	C5H4N2O4
Baaritaan	99%
Muuqaalka	Budada cad
Lambarka CAS.	65-86-1
Baakad	25KG
Muddada Khafiska	2 sano
Kaydinta	Ku kaydi meel qabow oo qalalan
Shahaadada	ISO.