Vitamin B12 (Mecobalamin) CAS: 13422-55-4 Soo saaraha

Methylcobalamin waa nooc ka mid ah coenzyme-ka gudaha ee B12, oo ka qaybqaata wareegga hal unug oo kaarboon ah, oo door muhiim ah ka ciyaara isku-darka habka falcelinta methyl-ka ee methionine homocysteine. Mid ka mid ah qaababka firfircoon ee bayoolojiga ah ee fitamiin B12; oo ku kala duwan oo keliya beddelka methyl ee kooxda cyano. Coenzyme-ka ayaa looga baahan yahay biosynthesis-ka methionine. Fiitamiin (hematopoietic). Waxaa loo isticmaalaa daaweynta cudurrada habdhiska neerfaha, yareynta xanuunka iyo kabuubyada, yareynta xanuunka degdegga ah, hagaajinta xanuunka ay keento spondylosis-ka ilmo-galeenka, daaweynta dhego la'aanta degdegga ah, iwm. Mecobalamin waxaa loo isticmaalaa daawada daaweynta cudurrada neerfaha ee durugsan, marka la barbar dhigo diyaarinta kale ee fitamiin B12, iyadoo si wanaagsan loogu wareejinayo unugyada neerfaha, iyada oo loo marayo falcelinta wareejinta methyl, waxay kor u qaadi kartaa aashitada nucleic, dheef-shiid kiimikaadka borotiinka, hagaajinta unugyada neerfaha ee dhaawacan. Geedi socodka aashitada aashitada aashitada ee homocysteine, waxay door ka ciyaartaa coenzyme-ka, gaar ahaan isku-darka deoxyuridine ee thymidine, kor u qaadista DNA-da iyo isku-darka RNA ee ka qaybgalka. Sidoo kale tijaabada unugyada glial, daawooyinku waxay hagaajin karaan dhaqdhaqaaqa methionine synthase waxayna kor u qaadi karaan isku-darka lipids-ka myelin ee lecithin. Hagaajinta dheef-shiid kiimikaadka unugyada neerfaha, waxay kor u qaadi kartaa fiilada dhidibka iyo isku-darka borotiinka, waxay ka dhigi kartaa heerka gaarsiinta borotiinka qalfoofka mid u dhow mid caadi ah, waxayna ilaalin karaan shaqooyinka axonal.