Tos-Gly-OSu CAS:68385-26-2

Tos-Gly-OSu waxay door muhiim ah ka ciyaartaa isku-darka peptide-ka iyadoo ah fal-gal muhiim ah oo loogu talagalay shaqeynta kooxaha amino. Joogitaanka kooxda tosyl iyo shaqada NHS waxay u oggolaaneysaa falcelinta amidation-ka ee xulashada ah inay dhacaan, taasoo awood u siineysa isku-darka peptide-yada ku jira glycine iyo molecules-ka kale ama dusha sare si la xakameeyey. Isku-darkani waa mid qiimo leh oo loogu talagalay abuurista isku-dhafka peptide-ka oo leh sifooyin gaar ah sida xasilloonida oo la hagaajiyay, milmida, ama awoodda bioconjugation. Horumarinta daawada, Tos-Gly-OSu waxaa loo isticmaali karaa in lagu abuuro isku-dhafka peptide-dawada, taasoo horseedi karta waxtarka daaweynta oo la xoojiyay, gaarsiinta bartilmaameedka ah, ama codsiyada ogaanshaha. Marka lagu daro doorkeeda ku jirta isku-darka peptide-ka, Tos-Gly-OSu waxay ka heshaa codsi cilmi-baaris proteomics iyo biochemical, halkaas oo loo isticmaali karo wax-ka-beddelka goobta gaarka ah ee borotiinnada, soo saarista maktabadaha peptide-ka, ama shaqeynta dusha sare ee baaritaannada bioanalytical-ka ee kala duwan. Kala-duwanaanshaheeda iyo is-waafajinta xaaladaha tijaabada ee kala duwan waxay ka dhigayaan qayb lama huraan ah oo lagu furfurayo isku-dhafka nidaamyada bayoolojiga iyo horumarinta faragelinta bartilmaameedka ah ee xaaladaha caafimaad ee kala duwan. Marka la soo koobo, Tos-Gly-OSu waxay u taagan tahay qalab qiimo leh oo loogu talagalay cilmi-baarayaasha ku jira isku-darka peptide, horumarinta daawada, iyo daraasadaha bayoolaji, iyadoo bixinaysa awoodda lagu habeeyo peptides-ka iyo borotiinnada leh sifooyin iyo shaqooyin gaar ah, taasoo gacan ka geysanaysa horumarinta daawada, bayotechnoolajiyadda, iyo farsamooyinka bayoconjugation.