Spironolactone CAS:52-01-7 Alaab-qeybiye Soo-saare

Spironolactone (Aldactone) waa isku-dhis asal ahaan loo sameeyay sidii antagonist mineralocorticoid waxaana loo isticmaalaa sidii wakiil kaadida iyo dhiig karka. Si kastaba ha ahaatee, marka la qaato qiyaaso badan, spironolactone wuxuu ku xidhaa receptor-ka androgen-ka. Dhaqanka caafimaad ahaan, waa antagonist androgen oo daciif ah oo loo isticmaalo in lagu daaweeyo hirsutism-ka haweenka iyadoo la xannibayo testosterone oo ku xidhan receptors-ka androgen-ka ee timaha. Isticmaalka spironolactone ee haweenka si loogu daaweeyo hirsutism ama bidaarta qaabka ragga waxay keeni kartaa heerarka potassium-ka ee dhiigga oo kordha; heerarkan waa in la hubiyaa 1 bil gudahood marka la bilaabo daawada. Spironolactone (Aldactone) wuxuu si qaab-dhismeed ahaan ula xiriiraa aldosterone wuxuuna u dhaqmaa sidii ka hortag tartan si looga hortago isku xidhka aldosterone ee borotiinka gaarka ah ee ku xidha unugyada.