Aashitada R-(+)-alpha-Lipoic CAS:1200-22-2 Alaab-qeybiye Soo-saare

Aashitada R-(+)-α-Lipoic waxaa la muujiyay inay si weyn u kordhiso oksaydhka pyruvate iyadoo baabi'inaysa oksaydhka aashitada dufanka leh ee ku jira hepatocytes-ka jiirka. Saamayntani waxay ka dhigaysaa aashitada R-(+)-α-Lipoic ikhtiyaar daaweyn oo rajo leh oo loogu talagalay daaweynta sonkorowga Nooca II. Waa antioxidant bayooloji ah oo leh hawlo prooxidant ah, awooddeeda daaweynta si weyn ayaa loo baarayaa, tusaale ahaan daaweynta cudurka Alzheimers. α-Lipoic acid waxaa loo isticmaalay halbeeg tixraac ah oo loogu talagalay falanqaynta aashitada α-lipoic ee ku jirta balaasmaha aadanaha iyadoo la adeegsanayo koromatografi dareere ah oo waxqabad sare leh oo lagu daray qalabka lagu ogaado elektaroonigga (HPLC-ECD), matrices cunto oo kala duwan iyo kaabisyo cunto oo ay samaysay HPLC oo ay weheliso qalabka lagu ogaado electrode coulometric (CEAD) iyo sidoo kale qalabka lagu cabbiro ionization mass ionization (ESI-MS). Waxaa loo isticmaali karaa halbeeg tixraac ah oo loogu talagalay go'aaminta aashitada α-lipoic ee kaadida aadanaha iyadoo la adeegsanayo HPLC marxaladda isocratic ee dib loo rogay iyo kaabsulka aashitada α-lipoic ee HPLC oo leh ogaanshaha chemiluminescence.