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N-Acetyl-D-Glucosamine CAS:7512-17-6 Alaab-qeybiye Soo-saare
N-Acetyl-D-Glucosamine waa wax soo saarka N-acetyl ee glucosamine. Kiimiko ahaan waa amide u dhexeeya glucosamine iyo acetic acid. Hal qayb oo N-acetlyglucosamine ah oo ku xiran haraaga serine ama threonine ee borotiinada nukliyeerka iyo cytoplasmic -O-GlcNAc, waa wax ka beddelka borotiinka ka dib tarjumaadda meel kasta. Borotiinnada wax laga beddelay ee O-GlcNAc waxay ku lug leeyihiin dareemidda xaaladda nafaqada ee deegaanka unugyada ee ku xeeran iyo hagaajinta dhaqdhaqaaqa borotiinnada unugyada si waafaqsan. O-GlcNAc waxay xakameysaa jawaabaha unugyada ee hoormoonnada sida insulin, waxay bilaabeysaa jawaab celin ilaalin ah oo ku saabsan walbahaarka, waxay beddeshaa awoodda unug si ay u koraan oo u qaybsamaan, waxayna nidaamisaa qoraalka hidda-wadaha. Aadanaha, waxay ku jirtaa maqaarka, carjawda iyo xididdada dhiigga iyadoo qayb ka ah hyaluronic acid, iyo unugyada lafaha, cornea iyo aorta oo qayb ka ah keratan sulfate.
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Creatine Pyruvate CAS:55965-97-4 Alaab-qeybiye Soo-saare
Creatine Pyruvate waa isku-darka ay ku jiraan Creatine iyo pyruvic acid waxaana dhisayaasha jirka u isticmaala kaabis ahaan si ay u helaan natiijooyin ergogenic ah waxayna si buuxda ugu milmaan biyaha. Qaabkeeda isku-dhafka ah Creatine Pyruvate wuxuu 10 jeer ka milmaa marka loo eego qaabkooda gaarka ah. Daraasadaha kiliinikada ayaa muujiyay in Pyruvate uu yareeyo baruurta jirka isagoon saameyn ku yeelan borotiinka muruqa, oo ah qayb muhiim ah oo lagu gaaro cufnaanta murqaha caatada ah. Kaabayaasha Creatine Pyruvate waa taageero nafaqo oo ku habboon ciyaartoyda raadinaya inay kordhiyaan waxqabadka murqaha iyo adkeysiga barnaamijyada jimicsiga ee xoogga badan.
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Fiitamiin A Palmitat CAS:79-81-2 Alaab-qeybiye Soo-saare
Retinyl palmitate waxay ka tirsan tahay qayb ka mid ah isku-dhafka loo yaqaan retinoids, kuwaas oo si kiimiko ah ula mid ah fitamiin A. Waxay leedahay saameyn faa'iido leh oo ku saabsan aragga, maqaarka iyo shaqada difaaca jirka, waxay joojisaa faafitaanka unugyada waxayna ka hortagtaa kansarka. Waa isku-darka cuntada muhiimka ah iyo sidoo kale isku-darka daaweynta. All-trans-retinyl palmitate waa isku-darka all-trans-retinyl ester oo laga helo isku-darka rasmiga ah ee kooxda carboxy ee palmitic (hexadecanoic acid) oo leh kooxda hydroxy ee all-trans-retinol. Waxaa loo isticmaalaa alaabada qurxinta si loogu daaweeyo cudurrada maqaarka ee kala duwan sida finanka, gabowga maqaarka, laalaabyada, dhibco madow, iyo sidoo kale ka ilaalinta cudurka psoriasis. Waxay leedahay door ah metabolite Escherichia coli, metabolite xenobiotic aadanaha iyo antioxidant. Waa retinyl palmitate iyo dhammaan-trans-retinyl ester. Waxay si shaqo leh ula xiriirtaa dhammaan-trans-retinol.
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Benfotiamine CAS:22457-89-2 Alaab-qeybiye Soo-saare
S-Benzoylthiamine O-monophosphate (Benfotiamine) waa nooc ka mid ah amphiphilic S-acyl thiamine. Waa fiitamiin milma dufanka. Benfotiamine waxa uu ka kooban yahay giraanta thiazole. Benfotiamine waxa uu leeyahay helitaan ka badan thiamine.
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Kolajeen Haydarooliga ah CAS:92113-31-0 Bixiyaha Soo-saaraha
Kolajka la qalajiyey ee la qalajiyey waxaa sidoo kale loo yaqaan kolajka la qalajiyey ee la qalajiyey. Kolajka la qalajiyey ee la dhalaaliyey waa nooc cusub oo kolajka ah, kaas oo laga soo saaro ilo kolajka ama kolajka hodanka ku ah. Marka laga soo tago halabuurka amino acid ee astaamaha u ah kolajka (qiyaastii 30% wadarta haraaga amino acid waa glycine), waxa kale oo uu leeyahay 15-30% laba amino acids oo si dhif ah looga helo borotiinnada kale, proline iyo 4-hydroxyproline Marka lagu daro aashitada), waxa kale oo uu leeyahay astaamaha miisaanka molecular-ka yar, halabuurkana waxa uu inta badan ka kooban yahay peptides yaryar oo miisaankoodu ka yar yahay 3000.
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Fiitamiin E Dabiici ah CAS:59-02-9 Alaab-qeybiye Soo-saare
Saliidda Fiitamiin E waa fiitamiin milma dufanka, oo sidoo kale loo yaqaan tocopherol. Waa mid ka mid ah antioxidants-ka ugu muhiimsan. Waa dareereyaal dabiici ah oo dufanku ku milmo sida ethanol, oo aan ku milmin biyaha, kulaylka, aashitada deggan, oo saldhig u ah. Waxay u nugul tahay oksijiinta laakiin ma aha mid xasaasi u ah kulaylka. Waxqabadka fitamiin E wuxuu ahaa mid aad u hooseeya oo shiilan.α-Tocopherol waxaa laga soo saaraa γ-tocopherol iyadoo la adeegsanayo ficilka enzyme γ-tocopherol methyltransferase. Waa qaabka ugu weyn ee Vitamin E ee ku jira plasma-ga aadanaha. Waxay ku jirtaa saliidda iniinaha gabbaldayaha.
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Curcumin (turmeric) 95% CAS:458-37-7 Alaab-qeybiye Soo-saare
Curcumin waa midabka jaalaha ah ee ugu weyn ee turmeric iyo curry wuxuuna leeyahay hawlo antioxidant, anti-barar, iyo antiburo. Waxay joojisaa soo saarista nitric oxide (NO) (IC50 = 6 μM) waxayna yareysaa dhaqdhaqaaqa nitric oxide synthase (iNOS) ee unugyada RAW 264.7 ee LPS kiciyay. Curcumin wuxuu joojiyaa sii deynta histamine iyo cytokines-ka bararka TNF-α, IL-1β, IL-6, iyo IL-8 ee unugyada HMC-1 mast. In vivo, curcumin wuxuu yareeyaa heerarka seeramka ee histamine iyo TNF-α, wuxuu joojiyaa isbeddellada histopathological ee xuubka sanka, wuxuuna yareeyaa tirada hindhisada iyo xoqidda sanka ee qaabka jiirka ee rhinitis-ka uu keeno ovalbumin.
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Fiitamiin B1 (Thiamine Hydrochloride) CAS:67-03-8 Alaab-qeybiye Soo-saare
Thiamine Hydrochloride waa nooca cusbada hydrochloride ee thiamine (vitamin B1), oo ah fiitamiin muhiim u ah dheef-shiid kiimikaadka aerobic, koritaanka unugyada, gudbinta dareen-celinta neerfaha iyo isku-darka acetylcholine. Faytamiin B1 wuxuu ka caawiyaa ka hortagga dhibaatooyin caafimaad oo kala duwan oo ay ku jiraan dhaawaca wadnaha.
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Hydroxycobalamin HCL CAS:78091-12-0 Bixiyaha Soo-saaraha
Hydroxycobalamin (ohcbl, ama B12a) waa nooc dabiici ah oo fiitamiin B12 ah, ama mid ka mid ah fasallada fitamiin B12. Waa xubin aasaasi ah oo ka tirsan kooxda cobalamine. Bakteeriyada badan ee soo saarta fiitamiinnada ganacsi ahaan waxay soo saaraan fiitamiin B12 qaab hydroxycobalamin ah. Hydroxycobalamin waa casaan madow. Faytamiin B12 ee jirka bini'aadamka caadi ahaan kuma jiro qaab hydroxycobalamin ah. Si kastaba ha ahaatee, aadanaha, hydroxycobalamin si fudud ayaa loogu beddelaa qaab coenzyme waxtar leh oo fiitamiin B12 ah. Badeecada daawada hydroxycobalamin waa duritaankeeda nadiifka ah, kaas oo loo isticmaalo in lagu daaweeyo yaraanta fitamiinka iyo sumowga cyanide (sababtoo ah waxay la jaanqaadaysaa ion-yada cyanide).
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Collagen II CAS:9064-67-9 Alaab-qeybiye Soo-saare
Kolajiinku waa qaybta ugu muhiimsan ee unugyada ka baxsan jirka kaas oo ah borotiin badan oo qaab-dhismeedka fibrous ah oo ku jira dhammaan qaybaha sare. Inta badan waxaa laga helaa unugyada fibrous sida maqaarka, seedaha iyo seedaha qaab fibrils dheer, sidoo kale wuxuu ku badan yahay cornea, xididdada dhiigga, lafaha, carjawda, saxanka intervertebral iyo mindhicirka. Kuwani waa borotiinka ugu badan ee ku jira naasleyda oo ka kooban in ka badan 30% borotiinka guud ee jirka xayawaanka.
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Nicotinamide Riboside (Kloride) CAS:23111-00-4 Alaab-qeybiye Soo-saare
Nicotinamide Riboside Chloride waa qaabka cusbada chloride ee nicotinamide riboside (NR).NR waa qaab cusub oo pyridine-nucleoside ah oo fiitamiin B3 ah kaas oo u shaqeeya sidii horudhac u ah nicotinamide adenine dinucleotide (NAD) ama NAD+. Nicotinamide riboside chloride waa qaab crystal ah oo ah Nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride waxay kordhisaa heerarka NAD[+] waxayna kicisaa SIRT1 iyo SIRT3, taasoo ku dambaynaysa dheef-shiid kiimikaad oksaydh oo la xoojiyay iyo ilaalinta cilladaha dheef-shiid kiimikaadka ee dufanka badan keena ee cuntada. Nicotinamide riboside chloride waxaa loo isticmaalaa kaabisyada cuntada.
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D-Fructose 1,6-Disphosphate Trisodium Cusbo CAS:38099-82-0
Fructose-1,6-biphosphate (F1,6P) waa dhexdhexaad glycolytic ah oo ay soo saarto wareejinta fosfate laga bilaabo ATP una gudubto fructose-6-phosphate iyadoo la adeegsanayo enzyme phosphofructokinase. Fructose-1,6-biphosphate, oo ay weheliso fructose-2,6-biphosphate, waxay wax ka beddeshaa dhaqdhaqaaqa phosphofructokinase-1 (PFK-1), oo ah tallaabada xaddidaysa heerka glycolysis. Inta lagu jiro glycolysis, aldolase wuxuu u kala qaybiyaa Fructose-1,6-biphosphate dihydroxacetone phosphate (DHAP) iyo glyceraldehyde phosphate. Fructose-1,6-biphosphate sidoo kale waa firfircooni allosteric ah oo ka mid ah isoform M2 ee Pyruvate Kinase (PK-M2), oo ah qaabka ugu badan ee pyruvate kinase ee unugyada kansarka.
