N-Acetyl-D-methionine CAS:1509-92-8

N-Acetyl-D-methionine waxaa loo isticmaalaa qayb muhiim ah oo ka mid ah soo saarista peptides-ka loo habeeyey iyo peptidomimetics sababtoo ah stereochemistry-ga gaarka ah, taasoo awood u siinaysa xakamaynta chiral-ka saxda ah ee taxanaha peptide-ka. Cilmi-baarayaasha iyo farmashiistayaashu waxay adeegsadaan N-Acetyl-D-methionine si ay u soo bandhigaan astaamo dhisme oo gaar ah ama kooxo shaqeynaya silsiladaha peptide-ka iyada oo loo marayo hababka isku-darka peptide-ka marxaladda adag iyo marxaladda xalka, taasoo sahlaysa horumarinta isku-dhafka bioactive-ka cusub iyo peptides-ka daaweynta ee bartilmaameedsanaya soo-dhoweeyayaasha bayoolojiga, ensaymyada, ama gaadiidleyda leh dhaqdhaqaaq bayooloji oo la xoojiyay iyo xasilloonida dheef-shiid kiimikaadka. Intaa waxaa dheer, N-Acetyl-D-methionine waxay ka heshaa codsi cilmi-baarista iyo horumarinta dawooyinka, halkaas oo sifooyinkeeda chiral ay gacan ka geystaan ​​​​sameynta musharixiinta daawada chiral iyo dhexdhexaadiyeyaasha dawooyinka. Astaamaha stereochemical-ga ayaa ka dhigaya mid aan lagama maarmaan u ah soo saarista alaabada dawooyinka, kor u qaadista sifooyinka daawada iyo hawlaha bayoolojiga ee isku-dhafka daawooyinka suurtagalka ah, taageeridda dadaallada lagu ogaanayo daawada iyo horumarinta wakiilada dawooyinka. Intaa waxaa dheer, N-Acetyl-D-methionine waxaa loo isticmaalaa daraasadaha bayoolaji si loo baaro dheef-shiid kiimikaadka methionine, isku-dhafka ka kooban sulfur, iyo waddooyinka unugyada ee ku lug leh biosynthesis borotiinka iyo homeostasis-ka unugyada. Doorkeeda ku aaddan qeexidda shaqooyinka methionine iyo enantiomers-keeda waxay gacan ka geysaneysaa fahamka saameynta ay ku leeyihiin hababka kala duwan ee jir ahaaneed, xaaladaha cudurrada, iyo faragelinta daaweynta ee suurtagalka ah. Marka la soo koobo, N-Acetyl-D-methionine waxay door muhiim ah ka ciyaartaa horumarinta cilmi-baarista sayniska, horumarinta daawooyinka, iyo daraasadaha bayoolaji, iyadoo siineysa saynisyahannada iyo xirfadlayaasha qalab kala duwan si ay u sahamiyaan codsiyada kala duwan ee methionine-ka ee soo saarista daawada, isku-darka peptide-ka, iyo baaritaannada bayoolaji.