Mirabegron CAS:223673-61-8 Alaab-qeybiye Soo-saare

Mirabegron waxaa loogu talagalay daaweynta degdegga ah, soo noqnoqoshada kaadida, iyo kaadida oo aan kaadida lahayn oo la xiriirta kaadiheysta firfircoon (OAB). Mirabegron waxaa lagu sameeyaa iyadoo la isku xidho 4-nitrophenethyl amine iyo (R)-2-hydroxy-2-phenylacetic acid. Amide-ka ka dhasha waxaa loo yareeyaa amine. Kooxda nitro-ga ayaa markaa la dhimaa natiijadana waxaa lagu xiraa 2-(2-aminothiazol-4-yl) acetic acid si loo siiyo mirabegron.

Dalbo ama Codso Qiimayn

Faahfaahinta Badeecada

Calaamadaha Alaabta

Codsiga iyo Saamaynta

Mirabegron waa β3-adrenoceptor agonist afka laga qaato oo hadda ay samaysay Astellas Pharma si loogu daaweeyo kaadiheysta firfircoon (OAB). Daawadu waa antagonist EC50 nanomolar ah oo ka soo horjeeda baaritaanka biochemical-ka ee β3-AR ee aadanaha oo leh xulasho wanaagsan marka loo eego b1- iyo β2-ARs. Mirabegron wuxuu muujinayaa farsamo cusub isagoo bartilmaameedsanaya β3-AR si loogu nasto kaadiheysta si uu u caawiyo maaraynta astaamaha OAB sida degdegga kaadida oo kordha iyo soo noqnoqoshada iyo kaadida oo aan degdeg ahayn. Si kastaba ha ahaatee, mirabegron waa cytochrome P450 2D6 inhibitor, waxayna soo bandhigaysaa walaac ku saabsan isdhexgalka daroogada-daroogada iyadoo la isticmaalayo substrate-yada kale ee cytochrome P450 2D6.

Muunadda Badeecada

Baakaynta Alaabta:

Macluumaad Dheeraad ah:

Halabuurka	C21H24N4O2S
Baaritaan	99%
Muuqaalka	Budada cad ilaa jaalle ah oo khafiif ah
Lambarka CAS.	223673-61-8
Baakad	25KG
Muddada Khafiska	2 sano
Kaydinta	Ku kaydi meel qabow oo qalalan
Shahaadada	ISO.