Mirabegron CAS: 223673-61-8 Soo saaraha Soo saaraha

Mirabegron waxaa loogu talagalay daawaynta degdega ah, inta jeer ee kaadida, iyo rabitaanka kaadi mareenka kaadida kaadida ee la xiriirta kaadiheysta firfircoonida badan (OAB).Mirabegron waxa lagu farsameeyaa iyadoo la isku xidhayo 4-nitrophenethyl amine ilaa (R) -2-hydroxy-2-phenylacetic acid.Natiijadii amide waxaa lagu soo koobay amin.Kooxda nitro ayaa markaa hoos loo dhigayaa natiijadana waxay ku xidhan tahay 2- (2-aminothiazol-4-yl) acetic acid si loo siiyo mirabegron.

Dalbo ama Codso Xigasho

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Mirabgron waa β3-adrenoceptor agonist oo hadda ku jira horumarinta Astellas Pharma ee daaweynta kaadiheysta firfircoonida (OAB).Daawadu waa antagonist EC50 nanomolar ah oo ka dhan ah bini'aadamka β3-AR baaritaanka biochemical oo leh xulasho wanaagsan oo ka badan b1- iyo β2-ARs.Mirabegron waxay soo bandhigaysaa hab cusub oo lagu beegsanayo β3-AR ee nasashada kaadiheysta si ay u caawiso maaraynta calaamadaha OAB sida degdegga kaadida oo kordhay iyo inta jeer iyo degdega kaadida.Si kastaba ha noqotee, mirabegron waa cytochrome P450 2D6 inhibitor, waxayna kor u qaadaa welwelka isdhexgalka daroogada-daroogada ee maamulka isku dhafan ee cytochrome P450 2D6 substrates kale.

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Halabuurka	C21H24N4O2S
Qiimayn	99%
Muuqashada	Caddaan ilaa budo jaale ah oo cirro leh
CAS Maya.	223673-61-8
Baakad	25KG
Nolosha shelf	2 sano
Kaydinta	Ku kaydi meel qabow oo qalalan
Shahaado	ISO.