Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS:328086-60-8

Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate waxaa loo isticmaalaa dhexdhexaad muhiim ah oo loogu talagalay isku-darka peptide derivatives iyo isku-dhafka dawooyinka. Kooxaheeda gaarka ah ee shaqeynaya iyo stereochemistry waxay bixiyaan marin istiraatiiji ah oo loogu talagalay peptides-ka adag iyo peptidomimetics oo leh firfircooni bayooloji oo suurtagal ah iyo sifooyin daawo u eg. Cilmi-baarayaashu waxay ka faa'iidaystaan ​​​​sifooyinkooda qaab-dhismeedka si ay u soo bandhigaan haraaga amino acid iyo qaybaha heterocyclic taxanaha peptide, iyagoo wax ka beddelaya is-dhexgalka bayoolojiga iyo gaar ahaanta bartilmaameedka. Isku-dhafkan wuxuu helaa codsiyada kiimikada peptide, halkaas oo ay u adeegto sidii baloog dhisme oo loogu talagalay isku-darka peptide, isu-imaatinka peptide-ka adag ee wejiga, iyo naqshadeynta daawada peptide. Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate wuxuu awood u siinayaa dhismaha maktabadaha peptide, mimetics-ka peptide, iyo daaweynta ku salaysan peptide-ka oo bartilmaameedsanaya waddooyin kala duwan oo bayooloji ah iyo bartilmaameedyo molecular ah. Doorkeeda wax ka beddelka iyo hagaajinta peptide-ka wuxuu gacan ka geystaa horumarinta musharixiinta cusub ee daroogada, ogaanshaha, iyo qalabka bayoolaji. Warshadaha dawooyinka, Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate waxaa loo isticmaalaa isku-darka daawooyinka peptidic, isku-xidhka peptide, iyo daawooyinka prodrugs-ka ku salaysan peptide. Ka qaybgalkeeda cilmi-baarista peptide iyo daahfurka daawada waxay suurtogal ka dhigaysaa sahaminta calaamadaynta peptide-ka ee dhexdhexaadka ah, isdhexgalka soo-dhoweeyaha, iyo faragelinta daaweynta ee meelaha sida kansarka, difaaca jirka, iyo neerfaha. Iyagoo ku daraya isku-darkaan qaab-dhismeedka peptide, saynisyahannadu waxay kor u qaadi karaan sifooyinka daawada, xasilloonida bayoolojiga, iyo xiriirka bartilmaameedka ee daawooyinka ku salaysan peptide, iyagoo ballaarinaya baaxadda daaweynta peptide iyo daawada shaqsiga ah.