methyl 4-oxo-3,4-dihydroquinazoline-7-carboxylate CAS:313535-84-1

Methyl 4-oxo-3,4-dihydroquinazoline-7-carboxylate wuxuu door muhiim ah ka ciyaaraa isku-darka daawooyinka, isagoo u adeegaya sidii hordhac muhiim ah oo loogu talagalay noocyo badan oo isku-dhafan oo bayooloji firfircoon. Qaab-dhismeedkeeda quinazoline waa qaab-dhismeed caadi ah oo laga helo daawooyin badan, oo ay ku jiraan wakiilada ka hortagga kansarka, antihistamines, iyo kinase inhibitors. Iyagoo ka faa'iideysanaya kala duwanaanta isku-dhafkan, farmashiistayaashu waxay heli karaan waddooyin badan oo macmal ah si ay u abuuraan musharixiinta daroogada cusub oo leh faa'iidooyin daaweyn oo suurtagal ah. Intaa waxaa dheer, ku-biirinta dadaallada helitaanka daawada waxay suurtogal ka dhigaysaa wax-ka-beddelka qaab-dhismeedka quinazoline si loo soo saaro waxyaabo ka soo jeeda sifooyin dawooyin oo la hagaajiyay, sida awoodda la hagaajiyay iyo xulashada. Intaa waxaa dheer, isku-dhafkan waxaa loo isticmaalaa cilmi-baarista tacliinta iyo goobaha warshadaha si loo sahamiyo hay'ado kiimiko oo cusub oo leh astaamo dawooyin oo rajo leh. Kalsoonida iyo isku-dheellitirka methyl 4-oxo-3,4-dihydroquinazoline-7-carboxylate waxay ka dhigaysaa qalab lama huraan ah warshadaha dawooyinka, iyagoo fududeynaya isku-darka hufan ee molecules-ka adag iyadoo la hubinayo natiijooyin la soo saari karo. Iyada oo ah qayb aasaasi ah oo ka mid ah kiimikada daawada, waxay awood u siinaysaa saynisyahannada inay ballaariyaan booska kiimikada ee musharixiinta suurtagalka ah ee daroogada iyo inay horumariyaan horumarinta daawaynta cusub ee xaaladaha caafimaad ee kala duwan.