Iodoacetamide CAS:144-48-9 Qiimaha Soo-saaraha

Wax-ka-beddelka Cysteine: Iodoacetamide wuxuu la falgalaa kooxaha thiol ee xorta ah ee ku jira haraaga cysteine, isagoo sameeya xiriir isku xiran oo la leh cysteine ​​sulfur. Wax-ka-beddelkani wuxuu ka caawiyaa falanqaynta borotiinka isagoo xannibaya haraaga cysteine ​​​​oo ka hortagaya falcelinta aan loo baahnayn ama oksaydhka.

Dheefshiidka Borotiinka: Iodoacetamide waxaa badanaa loo isticmaalaa hababka dheefshiidka borotiinka ee falanqaynta spectrometry-ga. Waxay la falgashaa haraaga cysteine ​​​​ka hor dheefshiidka enzymatic, iyadoo ka hortageysa sameynta isku xirnaanta disulfide ee aan loo baahnayn waxayna ku haysaa borotiinka xaaladdiisa hoos u dhacday.

Daraasadaha Proteomics: Iodoacetamide waxaa loo isticmaalaa istaraatiijiyadaha calaamadaynta ee ku lug leh proteomics-ka ku salaysan cufnaanta spectrometry. Iyada oo loo marayo falcelinta haraaga cysteine, waxay suurtogal ka dhigaysaa calaamadaynta xulashada iyo aqoonsashada peptides-ka ku jira cysteine.

Daraasadaha Qaab-dhismeedka Borotiin: Iodoacetamide waxaa loo isticmaalaa daraasadaha qaab-dhismeedka si loogu beddelo haraaga cysteine-ka kiimikada loona barto shaqadooda iyo ka qaybgalkooda isbeddellada laablaabashada borotiinka, isku xidhka, iyo qaab-dhismeedka. Waxa kale oo ay faa'iido u yeelan kartaa tijaabooyinka isku xidhka si loo sawiro isdhexgalka borotiinka-borotiin.

Isku-darka Peptides-ka Calaamadaysan: Iodoacetamide waxaa loo isticmaali karaa in lagu sameeyo peptides-ka calaamadaysan iyadoo wax laga beddelayo haraaga cysteine-ka oo leh isku-dhisyo si gaar ah loogu calaamadeeyay, sida deuterium ama carbon-13. Peptides-kan calaamadaysan ayaa markaa loo isticmaalaa codsiyo cilmi-baaris oo kala duwan, oo ay ku jiraan cabbirka borotiinka iyo daraasadaha firfircoonida.