Ibandronate Sodium CAS: 138844-81-2 Soo saaraha soo saaraha Sawirka

Ibanbronate Sodium CAS: 138844-81-2 Soo saaraha

Isodium bandronate (BONIVA) waa bisfosphonate nitrogen ka kooban oo joojisa dib-u-soo-celinta lafaha osteoclast-dhexdhexaadin ah.BONIVA waxa kale oo ku jira maadooyinka soo socda ee aan firfircoonayn: lactose monohydrate, povidone, microcrystalline cellulose, crospovidone, stearic acid la safeeyey, kolloidal silicon dioxide, iyo biyo la safeeyey.Dahaarka filimka kiniiniga ah wuxuu ka kooban yahay hypromellose, titanium dioxide, talc, polyetylen glycol 6000, iyo biyo nadiif ah.

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Codsiga iyo Saamaynta

Ibanbronate sodium ayaa loo isticmaalay in lagu barto saamaynta ay ku leedahay fidinta iyo qaabdhismeedka sare ee Leishmania iyo Giardia ee jiilka fiirsashada.Waxa kale oo loo isticmaalay in lagu caddeeyo dariiqa ay ku jiraan bisfosphonates nitrogen-ku jira (N-BPs) waxay galaan cytosol waxayna joojiyaan bartilmaameedkooda molecular.Ibandronate sodium waxay joojisaa farnesyl diphosphate synthase (IC50 = 20 nM).Ibandronate sodium sidoo kale waa lafaha resorption inhibitor.Waxaa lagu baadhay in vitro saamaynta anti-buro, sida induction apoptosis, inhibitor koritaanka unugga, ka hortagga dabeecadda invasive, iyo ka hortagga angiogenesis iyo doorkeeda in vivo ee kansarrada kala duwan oo ay ku jiraan kansarka naasaha iyo qanjirka 'prostate'.