H-Ile-OBzl·Tos CAS:16652-75-8

H-Ile-OBzl·Tos waxay u adeegtaa sidii baloog dhisme oo muhiim ah oo ku jira isku-darka peptide-ka, iyadoo door muhiim ah ka ciyaareysa dhismaha peptide-yada leh astaamo qaab-dhismeed iyo shaqo oo gaar ah. Joogitaanka kooxda ilaalinta benzyl waxay hubineysaa in haraaga isoleucine uusan isbeddelin inta lagu jiro hababka isku-darka peptide-ka, taasoo u oggolaaneysa isu-imaatinka peptide-ka saxda ah oo la xakameeyey. Kooxda tosyl waxay fududeysaa falcelinta amidation-ka ee xulashada ah, taasoo awood u siineysa isku-darka peptide-yada ka kooban isoleucine iyo molecules-ka kale ama dusha sare si la xakameeyey. Isku-darkani waa mid qiimo leh oo loogu talagalay abuurista isku-xidhka peptide-ka oo leh sifooyin gaar ah sida xasilloonida la hagaajiyay, milmida, ama awoodda bioconjugation-ka. Marka laga soo tago doorkeeda ku aaddan isku-darka peptide-ka, H-Ile-OBzl·Tos waxay ka heshaa codsi cilmi-baarista proteomics iyo biochemical, halkaas oo loo isticmaali karo wax-ka-beddelka goobta gaarka ah ee borotiinnada, soo saarista maktabadaha peptide-ka, ama shaqeynta dusha sare ee baaritaannada bioanalytical-ka ee kala duwan. Kala-duwanaanshaheeda iyo is-waafajinta xaaladaha tijaabada ee kala duwan waxay ka dhigayaan qayb lama huraan ah oo lagu furfurayo isku-dhafka nidaamyada bayoolojiga iyo horumarinta faragelinta bartilmaameedka ah ee xaaladaha caafimaad ee kala duwan. Guud ahaan, H-Ile-OBzl·Tos waxay u taagan tahay qalab qiimo leh oo loogu talagalay cilmi-baarayaasha ku jira isku-darka peptide, horumarinta daawada, iyo daraasadaha bayoolaji, iyagoo siinaya awoodda lagu habeeyo peptides-ka sifooyin iyo shaqooyin gaar ah, taasoo gacan ka geysaneysa horumarinta daawada, bayotechnoolajiyadda, iyo farsamooyinka isku-xidhka bayoolojiga.