H-His-OMe·2HCl CAS:7389-87-9

H-His-OMe·2HCl waxay u adeegtaa sidii baloog dhisme oo muhiim ah oo ku jira isku-darka peptide-ka, iyadoo door muhiim ah ka ciyaareysa dhisidda peptide-yada leh astaamo qaab-dhismeed iyo shaqo oo gaar ah. Joogitaanka kooxda methyl ester-ka iyo cusbooyinka hydrochloride waxay hubineysaa in haraaga histidine uusan isbeddelin inta lagu jiro hababka isku-darka peptide-ka, taasoo u oggolaaneysa isu-imaatinka peptide-ka saxda ah oo la xakameeyey. Isku-darkani waa mid qiimo leh oo loogu talagalay naqshadeynta peptide-yada leh sifooyin loo habeeyay sida xasilloonida la hagaajiyay, milmida, ama helitaanka bioavailability, taasoo ka dhigaysa qalab muhiim u ah horumarinta daawada, gaar ahaan abuurista daawooyinka ku salaysan peptide-ka oo leh waxtarka daaweynta oo la xoojiyay sababtoo ah qaabka milixda. Marka laga soo tago doorkeeda ku aaddan isku-darka peptide-ka, H-His-OMe·2HCl waxay ka heshaa codsi cilmi-baaris proteomics iyo biochemical, halkaas oo loo isticmaali karo in lagu barto isdhexgalka borotiinka-borotiinka, lagu baaro hawlaha ensaymikada, iyo in la sahamiyo dhaqdhaqaaqa laablaabashada borotiinka. Qaab-dhismeedkeeda loo habeeyay wuxuu u oggolaanayaa cilmi-baarayaasha inay baaraan isku-dhafka hababka unugyada iyo hababka cudurka, iyagoo gacan ka geysanaya horumarka fahamka caafimaadka iyo cudurada. Kala duwanaanta isku-dhafka ah iyo iswaafajinta xaaladaha tijaabada ee kala duwan ayaa ka dhigaya qayb lama huraan ah oo lagu furfurayo isku-dhafka nidaamyada bayoolojiga iyo horumarinta faragelinta bartilmaameedsan ee xaaladaha caafimaad ee kala duwan. Marka la soo koobo, H-His-OMe·2HCl waxay u taagan tahay qalab qiimo leh oo loogu talagalay cilmi-baarayaasha ku jira isku-darka peptide, horumarinta daawada, iyo daraasadaha bayoolojiga, iyadoo bixinaysa awoodda lagu habeeyo peptides-ka sifooyin gaar ah iyo in la furo hababka aasaasiga ah ee hababka bayoolojiga, taasoo gacan ka geysanaysa horumarka daawada iyo bayotechnoolajiyadda.