Glucose-6-Fosphate Dehydrogenase CAS:9001-40-5 Sawirka La Soo Bandhigay

Gulukoos-6-Fosfate Dehydrogenase CAS:9001-40-5

Glucose-6-phosphate dehydrogenase (G6PD) waa ensaym ku lug leh habka dheef-shiid kiimikaadka gulukooska. Waxay door muhiim ah ka ciyaartaa soo saarista NADPH, oo ah molecule muhiim u ah hababka kala duwan ee unugyada, oo ay ku jiraan difaaca antioxidant-ka iyo bayosynthesis-ka asiidhyada dufanka leh iyo kolestaroolka.

G6PD wuxuu kiciyaa beddelka gulukooska-6-phosphate ilaa 6-phosphogluconolactone, isagoo isla markaana hoos u dhigaya NADP+ una beddelaya NADPH. Falcelintani waxay muhiim u tahay ilaalinta sahay ku filan oo NADPH ah oo ku jirta unugyada, taas oo looga baahan yahay dheelitirka redox-ka unugyada iyo ilaalinta waxyeelada oksaydhka.

Dalbo ama Codso Qiimayn

Faahfaahinta Badeecada

Calaamadaha Alaabta

Codsiga iyo Saamaynta

Dheef-shiid kiimikaadka Unugyada: G6PD wuxuu ku lug leeyahay habka dheef-shiid kiimikaadka gulukooska, gaar ahaan habka pentose fosfate. Waxay kicisaa beddelka gulukooska-6-phosphate ilaa 6-phosphogluconolactone, taasoo soo saarta NADPH habka. NADPH waa molecule muhiim u ah hababka kala duwan ee unugyada, oo ay ku jiraan difaaca antioxidant-ka, biosynthesis-ka asiidhyada dufanka leh iyo kolestaroolka, iyo ilaalinta dheelitirka redox-ka unugyada.

Difaaca Ka-hortagga oksaydheynta: NADPH oo ay soo saarto G6PD ayaa muhiim u ah soo saarista glutathione-ka la dhimay (GSH), oo ah molecule muhiim u ah oksaydheynta. GSH waxay ka ilaalisaa unugyada walbahaarka oksaydhka iyadoo dhexdhexaadinaysa xagjirrada xorta ah iyo noocyada oksijiinta ee falcelinta leh (ROS). Yaraanta G6PD waxay wax u dhimi kartaa helitaanka NADPH waxayna yareyn kartaa hufnaanta difaaca oksaydhka, taasoo horseedi karta u nuglaanshaha sii kordheysa ee dhaawaca oksaydhka.

Dhiig-yaraanta Hemolytic: Yaraanta G6PD waa yaraanta ensaymka ugu badan adduunka oo dhan. Waxay inta badan saamaysaa ragga waxayna keeni kartaa dhiig-yaraanta hemolytic, xaalad lagu garto burburka unugyada dhiigga cas. Waxyeello gaar ah, sida caabuqyada, daawooyinka qaarkood (tusaale ahaan, daawooyinka ka hortagga duumada, daawooyinka sulfa), iyo cuntooyinka qaarkood (tusaale ahaan, digirta fava), waxay sababi karaan dhiig-yaraanta dadka qaba yaraanta G6PD. Yaraanta waxay sababtaa awood la'aan lagu maareeyo walbahaarka oksaydhka ee ay keenaan kiciyeyaashan, taasoo keenta burburka unugyada dhiigga cas.

Daawada Kiliinikada: Baaritaanka G6PD waa muhiim farmashiyada kiliinikada si looga hortago falcelinta daawada ee xun. Daawooyinka qaar, sida dawooyinka lidka ku ah duumada qaarkood (tusaale ahaan, primaquine) iyo antibiyootikada (tusaale ahaan, sulfonamides), waxay sababi karaan hemolysis shakhsiyaadka qaba yaraanta G6PD. Baaritaanka hore ee yaraanta G6PD wuxuu ka caawiyaa aqoonsashada shakhsiyaadka khatarta ku jira wuxuuna hagi karaa doorashada daawooyinka ama isticmaalka daawaynta kale si looga hortago dhacdooyinka hemolytic ee daran.

Baakaynta Alaabta:

Macluumaad Dheeraad ah:

Halabuurka	NA
Baaritaan	99%
Muuqaalka	Budada cad
Lambarka CAS.	9001-40-5
Baakad	Yar iyo weyn
Muddada Khafiska	2 sano
Kaydinta	Ku kaydi meel qabow oo qalalan
Shahaadada	ISO.