Fmoc-Gln-OH CAS:118609-68-0

Fmoc-Gln-OH waxay u adeegtaa sidii qalab kala duwan oo ku jira isku-darka peptide-ka, gaar ahaan sameynta peptides-ka ay ku jiraan glutamine si sax ah. Kooxda ilaalinta Fmoc waxay ilaalisaa kooxda amino-ka, iyadoo hubinaysa falcelinta xulashada ah inta lagu jiro isku-xidhka peptide-ka. Cilmi-baarayaashu si ballaaran ayay u isticmaalaan Fmoc-Gln-OH si ay u sameeyaan peptides-ka codsiyada kala duwan, oo ay ku jiraan horumarinta daaweynta ku salaysan peptide-ka, walxaha bayoolajiga, iyo peptides-ka oo leh qaabab dhismeed gaar ah. La jaanqaadkeeda hababka isku-darka peptide-ka caadiga ah, labadaba istiraatiijiyadaha wejiga adag iyo marxaladda xalka, waxay kor u qaadaysaa kala-duwanaanshaheeda dadaallada cilmi-baarista ee kala duwan. Ka saarista la xakameeyey ee kooxaha ilaalinta waxay u oggolaanaysaa ku-darka istaraatiijiyadeed ee glutamine taxanaha peptide-ka, iyadoo ballaarinaysa baaxadda peptide-yada la isku-darka karo. Intaa waxaa dheer, Fmoc-Gln-OH waxay ka heshaa faa'iido daraasadaha la xiriira injineernimada borotiinka, mimetics-ka peptide-ka, iyo naqshadeynta peptide-yada firfircoon. Isticmaalkeeda istaraatiijiyadeed wuxuu suurtogal ka dhigayaa maaraynta saxda ah ee falcelinta glutamine, isagoo siinaya cilmi-baarayaasha qalab qiimo leh oo loogu talagalay naqshadeynta peptides-ka oo leh wax-ka-beddello loo habeeyay. Marka la soo koobo, Fmoc-Gln-OH waxay u taagan tahay aalad aasaasi ah oo aan laga maarmi karin kiimikada peptide, taasoo awood siinaysa cilmi-baarayaasha inay sahamiyaan oo ay wax ka beddelaan falcelinta glutamine si loogu isticmaalo codsiyo cilmiyeed oo ballaaran, gaar ahaan diiradda saarista peptides-ka ka kooban amino acid-kan muhiimka ah.