Fmoc-D-Gln-OH CAS:71989-20-3

Fmoc-D-Gln-OH waxay u adeegtaa sidii qalab gaar ah oo ku jira isku-darka peptide, oo si gaar ah loogu talagalay in lagu sameeyo peptides ka kooban D-glutamine si sax ah. Kooxda ilaalinta Fmoc waxay ilaalisaa kooxda amino, iyadoo hubinaysa falcelinta xulashada inta lagu jiro isku-xidhka peptide, halka ku-darka D-enantiomer uu ku darayo cabbir gaar ah peptides-ka la sameeyay. Cilmi-baarayaashu si ballaaran ayay u adeegsadaan Fmoc-D-Gln-OH si ay u sameeyaan peptides-ka codsiyada kala duwan, oo ay ku jiraan daraasado ku lug leh asiidhyada D-amino, daaweynta ku salaysan peptide, iyo peptides-ka firfircoon ee noolaha oo leh qaabab dhismeed gaar ah. La jaanqaadkeeda hababka isku-darka peptide-ka caadiga ah, labadaba istiraatiijiyadaha wejiga adag iyo marxaladda xalka, waxay kor u qaadaysaa kala-duwanaanshaheeda dadaallada cilmi-baarista ee kala duwan. Ka saarista la xakameeyey ee kooxaha ilaalinta waxay u oggolaanaysaa ku-darka istaraatiijiyadeed ee D-glutamine taxanaha peptide, iyadoo ballaarinaysa fursadaha lagu sameeyo peptides-ka oo leh stereochemistry-ga la beddelay. Intaa waxaa dheer, Fmoc-D-Gln-OH waxay ka heshaa faa'iido daraasadaha la xiriira peptidomimetics, halkaas oo isticmaalka asiidhyada D-amino ay ku siin karaan xasillooni iyo firfircooni bayooloji oo la beddelay peptides-ka la sameeyay. Isticmaalka istaraatiijiyadeed ee Fmoc-D-Gln-OH wuxuu suurtogal ka dhigayaa in si sax ah loo maareeyo falgalka D-glutamine, isagoo siinaya cilmi-baarayaasha qalab qiimo leh oo loogu talagalay naqshadaynta peptides leh astaamo gaar ah oo stereochemical ah. Marka la soo koobo, Fmoc-D-Gln-OH waxay u taagan tahay qalab gaar ah oo aan laga maarmi karin oo ku jira kiimikada peptide, taasoo awood siinaysa cilmi-baarayaasha inay sahamiyaan oo ay wax ka beddelaan falgalka D-glutamine ee codsiyada sayniska ee gaarka ah, gaar ahaan diiradda saarista peptides-ka ka kooban qaabkan enantiomeric ee amino acid-ka muhiimka ah.