Fmoc-D-Asn-OH CAS:108321-39-7

Fmoc-D-Asn-OH waa ciyaaryahan muhiim ah oo ku jira isku-darka peptide-ka, gaar ahaan isku-darka la xakameeyey ee peptide-yada ka kooban D-enantiomer ee asparagine. Kooxda ilaalinta Fmoc waxay ilaalisaa kooxda amino-ka, iyadoo hubinaysa falcelinta xulashada inta lagu jiro isku-xidhka peptide-ka. Isku-darkani wuxuu si ballaaran u isticmaalaa isku-darka peptide-yada daraasadaha bayoolojiga, horumarinta daawada, iyo naqshadeynta peptide-yada firfircoon ee leh qaab-dhismeedyo gaar ah oo stereochemical ah. Kala-duwanaanshaha Fmoc-D-Asn-OH wuxuu ku fidsan yahay codsigiisa dhismaha peptide-yada leh haraaga D-asparagine, taasoo gacan ka geysanaysa horumarinta peptide-yada leh qaab-dhismeedyo iyo shaqooyin loo habeeyay. Cilmi-baarayaashu waxay ka faa'iidaystaan ​​​​iswaafajinta hababka isku-darka peptide-ka caadiga ah, iyagoo u adeegsanaya xeelado kala duwan oo isku-darka peptide-ka. Xasilloonida iyo fududaynta wax-ka-beddelka ayaa ka dhigaya doorasho la doorbidayo oo lagu soo saaro peptide-yada leh wax-ka-beddel sax ah, gaar ahaan kuwa ku lug leh asiidhyada D-amino. Intaa waxaa dheer, Fmoc-D-Asn-OH waxay u heshaa faa'iido ku jirta isku-darka peptide-yada walxaha bayoolojiga, cilmi-baarista proteomics, iyo daraasadda hababka unugyada, halkaas oo ku-darka asiidhyada D-amino ay ku siin karaan sifooyin gaar ah. Ilaalinta la xakameeyey ee kooxda Fmoc waxay u oggolaanaysaa istaraatiijiyadda ku darista D-asparagine taxanaha peptide. Marka la soo koobo, Fmoc-D-Asn-OH waxay u taagan tahay aalad badan oo aan laga maarmi karin oo ku jirta kiimikada peptide, iyadoo horumarinaysa cilmi-baarista iyo codsiyada qaybaha kala duwan ee sayniska iyadoo diiradda la saarayo peptides-ka ay ku jiraan D-amino acid.