Fmoc-Asn(Trt)-OH CAS:132388-59-1

Fmoc-Asn(Trt)-OH waxay ku leedahay boos dhexe isku-darka peptide-ka, gaar ahaan isku-darka xakamaynta ee peptide-yada ku jira asparagine. Kooxda ilaalinta Fmoc waxay ilaalisaa kooxda amino-ka, iyadoo hubinaysa falcelinta xulashada ah inta lagu jiro isku-xidhka peptide-ka, halka kooxda trityl-ku ay bixiso lakab dheeraad ah oo ilaalin ah. Cilmi-baarayaashu si weyn ayay u adeegsadaan Fmoc-Asn(Trt)-OH isku-darka peptide-yada codsiyada kala duwan, oo ay ku jiraan horumarinta daawada, walxaha bayoolajiga, iyo naqshadeynta peptide-yada firfircoon. La jaanqaadkeeda hababka isku-darka peptide-ka caadiga ah, labadaba istaraatiijiyadaha marxaladda adag iyo marxaladda xalka, waxay kor u qaadaysaa faa'iidadooda dadaallada cilmi-baarista ee kala duwan. Ka saarista la xakameeyey ee kooxaha ilaalinta waxay u oggolaanaysaa ku-darka istaraatiijiyadeed ee asparagine taxanaha peptide-ka, taasoo gacan ka geysanaysa kala duwanaanshaha peptide-yada la samayn karo. Intaa waxaa dheer, Fmoc-Asn(Trt)-OH waxay ka heshaa faa'iido isku-darka peptide-yada cilmi-baarista proteomics-ka iyo daraasadda hababka unugyada. Isticmaalka istaraatiijiyadeed ee kooxda ilaalinta trityl wuxuu suurtogal ka dhigayaa in si sax ah loo maareeyo falcelinta asparagine, isagoo siinaya cilmi-baarayaasha qalab qiimo leh oo loogu talagalay naqshadeynta peptides-ka leh isbeddello gaar ah. Marka la soo koobo, Fmoc-Asn(Trt)-OH waxay u taagan tahay aalad badan oo aan laga maarmi karin oo ku jirta kiimikada peptide-ka, taasoo awood siinaysa cilmi-baarayaasha inay sahamiyaan oo ay wax ka beddelaan falcelinta asparagine ee codsiyo cilmiyeed oo ballaaran.