-
tert-butyl 4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate CAS: 932398-74-8
Tert-butyl 4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate, oo badanaa loo yaqaan isku-darka Y, waa isku-dhis kiimiko oo kala duwan oo leh codsiyo muhiim ah warshadaha daawada iyo sayniska agabka. Iyada oo leh qaacido molecular ah oo ah C15H21NO3, isku-darkani wuxuu leeyahay qaab-dhismeed quinoline gaar ah oo lagu beddelay koox tert-butyl ah iyo shaqo carboxylate ah. Qaab-dhismeedkeeda gaarka ah wuxuu bixiyaa sifooyin la jecel yahay oo muhiim u ah codsiyada kala duwan, laga bilaabo isku-darka daawada ilaa kiimikada agabka. Iyada oo ah dhexdhexaad muhiim ah oo ku jirta isku-darka dabiiciga ah, waxay u adeegtaa aasaaska horumarinta daawooyinka cusub iyo agabka shaqeynaya, taasoo horseedda hal-abuurka qaybaha kala duwan.
-
Semaglutide CAS:910463-68-2
Semaglutide waa peptide-1 (GLP-1) oo ah agonist receptor ah oo awood leh oo loo isticmaalo daaweynta nooca 2aad ee sonkorowga mellitus iyo cayilka. Iyada oo qaab-dhismeed ahaan la mid ah hoormoonka GLP-1 ee asalka ah, semaglutide wuxuu bixiyaa firfircooni daawo oo dheer sababtoo ah wax ka beddelka silsilad dhinaca aashitada dufanka leh. Iyada oo leh qaacidada molecular-ka C187H291N45O59, cimriga badhtamaha ee semaglutide wuxuu u oggolaanayaa qiyaas hal mar toddobaadkii ah, taasoo kor u qaadaysa ku habboonaanta bukaanka iyo u hoggaansanaanta nidaamyada daaweynta.
-
Linaclotide CAS:851199-59-2
Linaclotide waa agonist guanylate cyclase-C (GC-C) oo loo isticmaalo daaweynta calool istaagga daba dheeraada iyo xanuunka mindhicirka ee xanaaqa leh ee calool istaagga (IBS-C). Linaclotide, oo qaab-dhismeed ahaan la mid ah peptide-ka guanylin ee gudaha, waxay si xushmad leh ugu xidhaa oo u hawlgelisaa soo-dhoweeyayaasha GC-C ee marinnada caloosha, taasoo horseedaysa dheecaanka dheecaanka xiidmaha oo kordha iyo waqtiga socodka oo degdeg ah. Iyada oo leh qaacidada molecular-ka C59H79N15O21S6, linaclotide waxay bixisaa hab bartilmaameedsan si loo yareeyo calool istaagga loona yareeyo raaxo-darrada caloosha ee la xiriirta IBS-C, iyadoo hagaajinaysa tayada nolosha bukaanada.
-
Liraglutide CAS:204656-20-2
Liraglutide waa peptide-1 (GLP-1) oo ah agonist receptor ah oo awood leh oo loo isticmaalo daaweynta nooca 2aad ee sonkorowga mellitus iyo cayilka. Iyada oo qaab-dhismeed ahaan la mid ah hoormoonka GLP-1 ee asalka ah, liraglutide waxay bixisaa firfircooni dawo oo dheer sababtoo ah wax ka beddelka silsiladda dhinaca aashitada dufanka leh. Iyada oo leh qaacidada molecular-ka C172H265N43O51, cimriga badh-nololeedka ee liraglutide wuxuu u oggolaanayaa qiyaasta hal mar maalintii, taasoo kor u qaadaysa ku habboonaanta bukaanka iyo u hoggaansanaanta nidaamyada daaweynta.
-
ethyl 4-(hydroxymethyl)-1H-pyrazole-5-carboxylate CAS:61453-49-4
Ethyl 4-(hydroxymethyl)-1H-pyrazole-5-carboxylate, oo ah isku-dhis kiimiko oo kala duwan, ayaa muhiimad weyn u leh qaybaha dawooyinka iyo kiimikada beeraha. Iyada oo la adeegsanayo qaacidada molecular-ka C8H10N2O3, waxay leedahay giraan pyrazole ah oo lagu beddelay koox ethyl ah, qayb hydroxymethyl ah, iyo shaqo carboxylate ah. Isku-darkani wuxuu u adeegaa sidii dhexdhexaad qiimo leh oo ku saabsan isku-darka dabiiciga ah, isagoo fududeynaya horumarinta daawooyinka kala duwan iyo kiimikooyinka beeraha. Qaab-dhismeedkeeda gaarka ah iyo kooxaha shaqeynaya waxay ka dhigayaan baloog dhisme oo kala duwan oo loogu talagalay isku-darka molecules-ka iyadoo la adeegsanayo codsiyo kala duwan, taasoo horseedaysa hal-abuur warshado badan.
-
Ethyl 4-cyanopiperidine-4-carboxylatehydrochloride CAS:123730-64-3
Ethyl 4-cyanopiperidine-4-carboxylate hydrochloride, oo ah isku-dhis kiimiko oo muhiim ah, ayaa caan ku ah warshadaha dawooyinka iyo beeraha. Iyada oo la adeegsanayo qaacidada molecular-ka C9H14ClNO2, waxay leedahay giraan piperidine ah oo lagu beddelay koox ethyl ah iyo qayb cyano ah, oo ay weheliso shaqo carboxylate ah, dhammaantoodna ku xiran ion chloride ah. Isku-darkani wuxuu u adeegaa sidii dhexdhexaad muhiim ah oo ku saabsan isku-darka dabiiciga ah, isagoo fududeynaya horumarinta daawooyinka kala duwan iyo kiimikooyinka beeraha. Qaab-dhismeedkeeda gaarka ah iyo kooxaha shaqeynaya waxay ka dhigayaan baloog dhisme oo kala duwan oo loogu talagalay isku-darka molecules-ka iyadoo la adeegsanayo codsiyo kala duwan, taasoo kor u qaadaysa hal-abuurka qaybaha kala duwan.
-
![methyl imidazo[1,5-a]pyridine-7-carboxylate CAS:1377829-50-9](https://cdn.globalso.com/xindaobiotech/HSUS81DS80Y35NTEZTU180.png)
methyl imidazo[1,5-a]pyridine-7-carboxylate CAS:1377829-50-9
Methyl imidazo[1,5-a]pyridine-7-carboxylate, oo ah isku-dhis kiimiko ah oo leh qaacidada molecular-ka C9H7N3O2, ayaa caan ku ah adeegsigeeda kala duwan ee qaybaha sayniska dawooyinka iyo agabka. Iyada oo leh qaab-dhismeedka imidazo-pyridine, waxay soo bandhigaysaa astaamo qaab-dhismeed oo gaar ah oo gacan ka geysta isticmaalkeeda kala duwan. Isku-darkani wuxuu u adeegaa sidii dhexdhexaad qiimo leh oo ku jira isku-darka dabiiciga ah, isagoo u dhaqma sidii aasaas u ah horumarinta daawooyinka iyo agabka shaqeynaya. Qaab-dhismeedkeeda gaarka ah iyo fal-celinta ayaa ka dhigaya qayb muhiim ah cilmi-baaris iyo dadaallo warshadeed oo kala duwan, taasoo horseedaysa hal-abuurka qaybaha kala duwan.
-
Arg34GLP-1 CAS:1169630-82-3
Arg34GLP-1, oo sidoo kale loo yaqaan Arginine-34 Glucagon-Like Peptide 1, waa hoormoon peptide ah oo firfircoon oo saameyn weyn ku leh habaynta dheef-shiid kiimikaadka iyo faragelinta daaweynta ee sonkorowga iyo cayilka. Peptide-kan waxaa laga soo qaatay hoormoonka glucagon-like peptide 1 (GLP-1) wuxuuna leeyahay haraaga arginine booska 34. Qaab-dhismeedkiisa molecular iyo hawlihiisa bayoolojiga ayaa ka dhigaya musharax rajo leh oo loogu talagalay codsiyada dawooyinka ee loogu talagalay hagaajinta homeostasis-ka gulukooska iyo kor u qaadista miisaanka oo yaraada.
-
1-tert-Butyl 4-ethyl 4-cyanopiperidine-1,4-dicarboxylate CAS:1016258-66-4
1-tert-Butyl 4-ethyl 4-cyanopiperidine-1,4-dicarboxylate waa isku-dhis kiimiko ah oo loo yaqaan adeegsigeeda kala duwan ee warshadaha dawooyinka iyo beeraha. Iyada oo la adeegsanayo qaacidada molecular-ka C15H24N2O4, waxay muujinaysaa qaab-dhismeed gaar ah oo leh giraan piperidine ah oo lagu beddelay kooxaha tert-butyl, ethyl, iyo cyano. Isku-darkani wuxuu u adeegaa sidii dhexdhexaad qiimo leh oo ku jira isku-darka dabiiciga ah, isagoo door muhiim ah ka ciyaara horumarinta daawooyinka kala duwan iyo kiimikooyinka beeraha. Qaabkeeda beddelka istaraatiijiyadeed iyo kooxaha shaqeynaya waxay ka dhigayaan baloog dhisme oo kala duwan oo lagu sameeyo qaab-dhismeedka molecular-ka ee isku dhafan oo leh sifooyin la jecel yahay oo loogu talagalay codsiyada kala duwan.
-
![6-Chloro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride CAS:1956310-17-0](https://cdn.globalso.com/xindaobiotech/VMLV8UWXAZ0XBLS6M117.png)
6-Chloro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride CAS:1956310-17-0
6-Chloro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride, oo loo yaqaan isku-dhafka X, waa isku-dhis kiimiko ah oo leh codsiyo kala duwan warshadaha daawada iyo sayniska agabka. Iyada oo leh qaacido molecular ah oo ah C8H8ClNO•HCl, isku-darkani wuxuu leeyahay qaab-dhismeed benzo[b][1,4]oxazine oo gaar ah oo lagu beddelay atamka chlorine. Qaab-dhismeedkeeda gaarka ah wuxuu ka dhigayaa mid qiimo leh oo ku jira isku-darka dabiiciga ah, isagoo u adeegaya aasaaska horumarinta daawooyinka kala duwan iyo agabka shaqada.
-
8-Methylquinazolin-4(3H)-one CAS:19181-54-5
8-Methylquinazolin-4(3H)-mid waa isku-dhis kiimiko ah oo leh codsiyo kala duwan oo ku saabsan kiimikada daawada iyo cilmi-baarista dawooyinka. Iyada oo leh qaacidada molecular-ka C9H8N2O, waxay ka tirsan tahay fasalka quinazolinone ee isku-dhisyada waxayna muujisaa sifooyin gaar ah oo fiisikokemikal ah oo ka dhigaya mid qiimo leh dadaallada daahfurka daroogada iyo daraasadaha xiriirka qaab-dhismeedka-dhaqdhaqaaqa ee horumarinta wakiilada daaweynta cusub.
-
5,6-Difluoro-2,3-dihydro-1H-isoindol-1-one CAS:1192040-50-8
5,6-Difluoro-2,3-dihydro-1H-isoindol-1-one, oo loo aqoonsaday sifooyinkeeda kala duwan, waxay u adeegtaa sidii isku-dhis muhiim ah oo ku jira cilmi-baarista iyo warshadaha labadaba. Iyada oo la adeegsanayo qaacidada kiimikada C8H6F2NO, waxay leedahay xudunta isoindolone gaar ah oo lagu beddelay laba atam oo fluorine ah, taasoo siinaysa astaamo kala duwan qaab-dhismeedkeeda. Isku-darkani wuxuu helaa codsiyo ku baahsan goobo kala duwan sababtoo ah falcelintiisa kala duwan iyo kartida uu u leeyahay inuu isku-dubaridka molecules-ka isku dhafan oo leh khuseyn cilmiyeed oo daawo iyo agab ah.
