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1 '1-Bis(diphenylphosphino)ferrocene Palladium(Ⅱ)chloride dichloromethane chloride CAS:95464-05-4
1,1-Bis(diphenylphosphino)ferrocene Palladium(II) Chloride Dichloromethane Complex, oo leh qaacidada kiimikada [Pd(dppf)Cl₂·CH₂Cl₂], waa isku-dhis organometallic ah oo ka kooban palladium(II) oo isku xiran ligand-ka dppf iyo chlorides-ka ku jira dareeraha dichloromethane. Waxaa si caadi ah loogu isticmaalaa isku-darka dabiiciga ah iyo katalisnimada.
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N-(6-bromopyridin-2-yl)thiourea CAS:439578-83-3
N-(6-Bromopyridin-2-yl)thiourea waa isku-dhis kiimiko ah oo lagu garto joogitaanka koox shaqo oo thiourea ah oo ku xiran qayb 6-bromopyridin-2-yl ah. Isku-darkani wuxuu xiiso u yeeshay kiimikada daawada sababtoo ah hawlihiisa kala duwan ee daawada iyo codsiyada daaweynta ee suurtagalka ah. Astaamaha qaab-dhismeedka gaarka ah waxay bixiyaan waddooyin lagu naqshadeeyo musharixiinta daroogada cusub oo leh bartilmaameedyo bayooloji oo gaar ah, taasoo ka dhigaysa hanti qiimo leh oo ku jirta helitaanka iyo horumarinta daawada.
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2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL CAS:269409-97-4
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, oo si caadi ah loogu yaqaan TMDBP, waa isku-dhis kiimiko ah oo ka tirsan fasalka esters-ka boron-ka phenolic. Qaab-dhismeedkeeda molecular-ka wuxuu ka kooban yahay koox phenolic hydroxyl ah oo ku xiran giraan phenyl ah oo sita qayb ester wareeg ah oo ka kooban boron. Isku-darkani wuxuu muhiimad u leeyahay isku-darka dabiiciga ah, gaar ahaan falgallada isku-xidhka isku-dhafka ah ee Suzuki-Miyaura, halkaas oo ay u adeegto sidii falgale boronate ah oo qiimo leh. Intaa waxaa dheer, qaab-dhismeedkeeda boronate ee wareegga deggan iyo dabeecadda sterically cakiran ayaa ka dhigaya mid faa'iido leh naqshadeynta ligands-ka si loogu sameeyo falgallada birta ee kala-guurka iyo horumarinta agabka shaqeynaya.
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1-Methyl-4-pyrazole boronic acid pinacol ester CAS:761446-44-0
1-Methyl-4-pyrazole boronic acid pinacol ester waa isku-dhis kiimiko ah oo loo kala saaray boronic ester. Qaab-dhismeedkeeda molecular wuxuu ka kooban yahay qayb ka mid ah boronic acid oo ku xiran giraanta pyrazole oo lagu beddelay kooxda pinacol ester (-OC(CH₃)₂C(CH₃)₂O-). Isku-darkani wuxuu muhiimad weyn u leeyahay isku-darka dabiiciga ah, gaar ahaan falgallada isku-xidhka ee Suzuki-Miyaura, halkaas oo ay u adeegto sidii falgale boronic ester oo kala duwan. Intaa waxaa dheer, xasilloonideeda, falcelinteeda xulashada ah, iyo iswaafajinta xaaladaha falcelinta kala duwan waxay ka dhigaysaa mid qiimo leh isku-darka dhexdhexaadiyeyaasha dawooyinka, kiimikooyinka beeraha, iyo agabka shaqada.
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![Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro-CAS:1784081-72-6](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG285.png)
Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro-CAS:1784081-72-6
Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- waa isku-dhis baaskiil-wadareed oo isku dhafan oo leh qaab-dhismeed asaasi ah oo cyclopenta[b]pyrrole ah iyo silsilad dhinaca hexahydro-1H-pyrrole-3a(1H)-methanol ah. Molekule-kani waa mid muhiim u ah kiimikada daawada sababtoo ah waxqabadyada dawooyinka ee suurtagalka ah. Qaab-dhismeedkeeda gaarka ah wuxuu bixiyaa fursado lagu horumarinayo musharixiinta daroogada cusub, gaar ahaan bartilmaameedsiga xanuunnada neerfaha iyo cudurrada kale halkaas oo wax-ka-beddelka soo-dhoweeyayaasha neerfaha iyo kuwa qaada ay muhiim tahay. Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- waxay u adeegtaa sidii saldhig u ah farmashiistayaasha daawada ee sahaminaya wakiillo daaweyn cusub oo leh sifooyin farmashiye-kinetic ah oo la hagaajiyay iyo waxyeellooyin yar.
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trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylicacid CAS:169248-97-9
Aashitada Trans-1-(tert-butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic waa molecule isku dhafan oo leh giraan pyrrolidine ah oo lagu beddelay kooxda tert-butoxycarbonyl booska 1aad iyo kooxda phenyl 3-(trifluoromethyl) booska 4aad. Isku-dhafkan wuxuu muhiimad u leeyahay kiimikada daawada, ugu horreyn sababtoo ah awooddiisa ah farmashiye ahaan naqshadeynta daawada. Qaab-dhismeedkeeda adag wuxuu soo bandhigayaa fursado lagu abuuro wakiillo daaweyn cusub oo leh sifooyin daawo oo loo habeeyay, gaar ahaan bartilmaameedsiga waddooyinka ku lug leh cudurrada bararka, kansarka, ama khalkhalka habdhiska neerfaha dhexe.
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(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1262849-90-0
(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride waa isku-dhis kiimiko ah oo lagu garto giraanta pyrrolidine oo lagu beddelay koox ethyl ah oo ku jirta booska 3-aad iyo kooxda tert-butyl ee booska 1-aad. Isku-darkani wuxuu soo jiitay dareenka kiimikada daawada sababtoo ah qaab-dhismeedkeeda stereochemical iyo codsiyada dawooyinka ee suurtagalka ah. Qaab-dhismeedkeeda gaarka ah wuxuu bixiyaa waddooyin lagu naqshadeeyo musharixiinta daroogada cusub oo leh bartilmaameedyo bayooloji oo gaar ah, taasoo ka dhigaysa hanti qiimo leh oo ku jirta helitaanka daawada iyo dadaallada horumarinta.
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Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1233501-65-9
Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride waa isku-dhis kiimiko ah oo lagu kala saaro giraanta pyrrolidine oo lagu beddelay kooxda ethyl ee booska 3-aad iyo kooxda tert-butyl ee booska 1-aad. Isku-darkani wuxuu soo jiitay dareenka kiimikada daawada sababtoo ah kakanaanta qaab-dhismeedka iyo codsiyada dawooyinka ee suurtagalka ah. Qaab-dhismeedkeeda gaarka ah wuxuu soo bandhigayaa fursado lagu naqshadeeyo musharixiinta daroogada cusub oo leh bartilmaameedyo bayooloji oo gaar ah, taasoo ka dhigaysa hanti qiimo leh oo ku jirta helitaanka daawada iyo dadaallada horumarinta.
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4-Hydroxyphenylboronic acid pinacol ester CAS:269409-70-3
4-Hydroxyphenylboronic acid pinacol ester, oo sidoo kale loo yaqaan 4-HPBA pinacol ester, waa isku-dhis kiimiko ah oo hoos yimaada qaybta esters-ka boronic. Qaab-dhismeedkeeda molecular-ka wuxuu ka kooban yahay qayb aashitada boronic ah oo ku xiran giraanta phenyl oo lagu beddelay kooxda pinacol ester (-OC(CH₃)₂C(CH₃)₂O-). Isku-darkani wuxuu muhiimad weyn u leeyahay isku-darka dabiiciga ah, gaar ahaan falgallada isku-xidhka Suzuki-Miyaura, halkaas oo ay u adeegto sidii fal-gale boric ester ah oo kala duwan. Intaa waxaa dheer, xasilloonideeda, fududaynta maaraynta, iyo iswaafajinta xaaladaha falcelinta kala duwan waxay ka dhigaysaa mid qiimo leh isku-darka dhexdhexaadiyeyaasha dawooyinka, alaabada dabiiciga ah, iyo agabka shaqeynaya.
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![Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5](https://cdn.globalso.com/xindaobiotech/HSUS81DS80Y35NTEZTU259.png)
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride waa isku-dhis kiimiko ah oo ka kooban koox shaqo oo carbate ah oo ku xiran giraanta piperidine oo lagu beddelay koox benzyl ah oo ku taal atamka nitrogen iyo koox propyl ah oo ku taal atamka kaarboonka. Isku-darkani wuxuu kiciyay xiisaha kiimikada daawada sababtoo ah kakanaanta qaab-dhismeedka iyo codsiyada dawooyinka ee suurtagalka ah. Qaab-dhismeedkeeda gaarka ah wuxuu bixiyaa fursado lagu naqshadeeyo musharixiinta daroogada cusub oo leh bartilmaameedyo bayooloji oo gaar ah, taasoo ka dhigaysa hanti qiimo leh oo ku jirta helitaanka daawada iyo dadaallada horumarinta.
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9,9-Dimethyl-9H-fluoren-2-yl-boronic aashito CAS:333432-28-3
Aashitada 9,9-Dimethyl-9H-fluoren-2-yl-boronic acid, oo inta badan loo yaqaan DMFBA, waa isku-dhis kiimiko ah oo ka tirsan fasalka aashitada boronic. Qaab-dhismeedkeeda molecular-ka wuxuu leeyahay qayb aashitada boronic ah oo ku xiran qaab-dhismeedka fluorene oo lagu beddelay laba kooxood oo methyl ah oo ku yaal booska 9-aad. Isku-darkani wuxuu muhiimad weyn u leeyahay isku-darka dabiiciga ah, gaar ahaan falgallada isku-xidhka isku-dhafka ah ee Suzuki-Miyaura, halkaas oo uu u dhaqmo sidii fal-gal aashitada boronic oo kala duwan. Intaa waxaa dheer, qaab-dhismeedkeeda adag iyo kan sterically-ka ah ayaa ka dhigaya mid qiimo leh naqshadeynta ligand ee falcelinta kala-guurka ee bir-ka-kicinta iyo horumarinta agabka shaqeynaya.
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4-Aashitada Carboxyphenylboronic CAS:14047-29-1
4-Carboxyphenylboronic acid, oo sidoo kale loo yaqaan 4-Carboxyphenylboronic acid ama 4-CPBA, waa isku-dhis kiimiko ah oo ka tirsan fasalka asiidhyada boronic. Waxaa lagu gartaa kooxda shaqada ee asiidhyada boronic (-B(OH)₂) oo ku xiran giraan phenyl ah oo lagu beddelay kooxda carboxylic acid (-COOH) ee booska para. Isku-darkani wuxuu helaa codsiyo ballaaran oo ku saabsan isku-darka dabiiciga ah, gaar ahaan falcelinta isku-xidhka isku-xidhka Suzuki-Miyaura si loo sameeyo isku-xidhka kaarboon-kaarboon. Intaa waxaa dheer, awooddeeda ay ugu xidhnaan karto diols iyo sonkortu waxay keentay in loo isticmaalo horumarinta dareemayaasha la socodka gulukooska iyo kiimikada daawada ee loogu talagalay naqshadeynta inhibitors ensaym iyo ligands receptor.
