Clascoterone CAS: 19608-29-8 Soo saaraha Soo saaraha

Clascoterone waa daawada daaweeyaha androgen-ka ee loo sameeyay kareemka jirka iyo xalalka Cassiopea (shirkad ka soo baxday Cosmo Pharmaceuticals) oo loogu talagalay daaweynta cudurrada maqaarka ku tiirsan ee androgen-ku-tiirsan, oo ay ku jiraan alopecia androgenetic alopecia iyo acne vulgaris.Inkasta oo habka saxda ah ee ficilka clascoterone ee daaweynta maqaarka ee finanka vulgaris aan la garanayn, daroogada ayaa la aaminsan yahay in ay la tartanto androgen dihydrotestosterone si loogu xiro reseptors androgen ee qanjidhada sebaceous iyo follicles timaha si loo yareeyo calaamadaha lagama maarmaanka u ah pathogenesis finan.

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Clascoterone waxaa loo soo saaray sidii kareem la mariyo by Cassiopea loogu talagalay cilladaha maqaarka ku tiirsan androgen-ku-tiirsan.Waxay ku xidhan tahay daaweeyayaasha androgen oo leh xidhiidh sare.Iyada oo la tartamaysa androgens si loogu xidho reseptors androgen, clascoterone waxay u shaqeysaa iyada oo xannibaysa calaamadaha soo-dhoweynta ee androgen receptor cascades kuwaas oo kor u qaada pathogenesis finanka, sida faafinta qanjidhada sebaceous, wax soo saarka sebum xad-dhaaf ah, iyo waddooyinka bararka.Bishii Agoosto 2020, FDA waxay ansixisay clascoterone ee fasalka koowaad ee daaweynta jirka la mariyo ee finanka ( finanka vulgaris ) ee bukaanka lab iyo dhedig ee 12 sano iyo ka weyn.Clascoterone sidoo kale waxaa loo baarayaa sidii daaweyn cusub oo loogu talagalay alopecia androgenetic.