Candesartan CAS: 139481-59-7 Soo saaraha Soo saaraha

Candesartan waa AT1 (angiotensin II reseptor 1) oo door ah.Antagonism of angiotensin reseptors waxay joojisaa vasoconstriction iyo soo saarista aldosterone, taasoo keenta hoos u dhac ku yimaada biyaha iyo soodhiyamka dhiiga.Waxay muujisaa saamaynta antihypertensive ee moodooyinka xayawaanka.Waxaa loo isticmaalaa daawaynta wadne-gabowga, sida antihypertensive.Candesartan ma saameynayso jiritaanka unugyada ama kororka laakiin waxay kordhisaa muujinta VEGF iyo interleukin-8 ee dhexdhexaadka dhaqanka ee unugyada KU-19-19.Candesartan (0.1 nM) waxay yarayn kartaa jawaabta ugu badan ee qandho ee angiostensin II qiyaastii 50%.