Boc-D-Tyr(Bzl)-OH CAS:63769-58-4

Boc-D-Tyr(Bzl)-OH waa qayb muhiim ah oo ka mid ah isku-darka peptide-ka, gaar ahaan isku-darka peptide-ka marxaladda adag (SPPS) iyo isku-darka peptide-ka marxaladda xalka. Maadaama ay tahay nooc ka mid ah D-amino acid oo la ilaaliyo oo ka kooban haraaga tyrosine oo lagu ilaaliyo kooxda benzyl ester, waxay sahlaysaa ku darista haraaga D-tyrosine taxanaha peptide. SPPS-ka, Boc-D-Tyr(Bzl)-OH waxaa loo isticmaalaa in si xushmad leh loogu soo bandhigo cutubyada D-tyrosine inta lagu jiro isku-darka tallaabooyinka silsiladaha peptide ee taageerooyinka adag, halka isku-darka marxaladda xalka, ay suurtogal ka dhigayso sameynta xidhmooyinka peptide ee falcelinta ku salaysan xalka. Cilmi-baarayaasha iyo saynisyahannada dawooyinka waxay adeegsadaan Boc-D-Tyr(Bzl)-OH si ay u abuuraan peptides loo habeeyay oo leh taxane gaar ah oo D-amino acid ah oo loogu talagalay baaritaannada bayoolojiga, daraasadaha qaab-dhismeedka, iyo horumarinta daawada. Iyagoo ka faa'iideysanaya sifooyinkeeda kiimikada, waxay gaari karaan isku-xidhnaan hufan oo ay la yeeshaan asiidhyada kale ee amino, taasoo horseedaysa fidinta la xakameeyey ee silsiladaha peptide iyo soo saarista qaab-dhismeedka peptide-ka kala duwan. Kala duwanaanta Boc-D-Tyr(Bzl)-OH waxay ka dhigaysaa aalad lama huraan ah oo dhinacyo kala duwan ah sida bayoolajiga, farmashiistaha, iyo bayoteknoolajiyadda. La jaanqaadkeeda hab-raacyada isku-darka peptide-ka caadiga ah, wax-soo-saarka sare, iyo waxqabadka la isku halleyn karo waxay gacan ka geystaan ​​​​isticmaalka ballaaran ee goobaha tacliinta iyo warshadaha. Hadday tahay mid lagu dabaqo cilmi-baarista aasaasiga ah ama dadaallada daahfurka daroogada, Boc-D-Tyr(Bzl)-OH waxay fududeysaa abuurista peptides-ka kuwaas oo saldhig u ah horumarka muhiimka ah ee sayniska bayoolajiga iyo hal-abuurka daaweynta.