Boc-D-Phe-ONp CAS:16195-70-9

Boc-D-Phe-ONp wuxuu door muhiim ah ka ciyaaraa isku-darka peptide, gaar ahaan isku-darka peptide-ka marxaladda adag (SPPS) iyo isku-darka peptide-ka marxaladda xalka. Iyada oo ah nooc ka soo jeeda amino acid oo la ilaaliyo, waxay sahlaysaa ku darista haraaga D-phenylalanine taxanaha peptide. SPPS, Boc-D-Phe-ONp waxaa loo isticmaalaa in si xushmad leh loogu soo bandhigo cutubyada D-phenylalanine inta lagu jiro isku-darka tallaabooyinka silsiladaha peptide ee taageerooyinka adag, halka isku-darka marxaladda xalka, ay suurtogal ka dhigayso sameynta xidhmooyinka peptide ee falcelinta ku salaysan xalka. Cilmi-baarayaasha iyo saynisyahannada dawooyinka waxay isticmaalaan Boc-D-Phe-ONp si ay u abuuraan peptides loo habeeyay oo leh taxane gaar ah oo D-amino acid ah oo loogu talagalay baaritaannada bayoolojiga, daraasadaha qaab-dhismeedka, iyo horumarinta daawada. Iyagoo ka faa'iideysanaya fal-celinta kooxda 4-nitrophenyl ester, waxay gaari karaan isku-xidhka hufan ee kooxaha amino, taasoo horseedaysa dheereynta la xakameeyey ee silsiladaha peptide iyo soo saarista qaab-dhismeedka peptide-ka kala duwan. Kala duwanaanta Boc-D-Phe-ONp waxay ka dhigaysaa qalab qiimo leh oo ku saabsan dhinacyo kala duwan sida bayoochemistry, farmashiyoolajiyada, iyo bayotechnoolajiyada. La jaanqaadkeeda hab-raacyada isku-darka peptide-ka caadiga ah, wax-soo-saar sare, iyo waxqabad la isku halleyn karo ayaa gacan ka geysta isticmaalkeeda ballaaran ee goobaha tacliinta iyo warshadaha. Hadday tahay mid lagu dabaqo cilmi-baarista aasaasiga ah ama dadaallada daahfurka daroogada, Boc-D-Phe-ONp waxay fududeysaa abuurista peptides-ka kuwaas oo saldhig u ah horumarka muhiimka ah ee sayniska bayoolajiga iyo hal-abuurka daaweynta.