Boc-D-MeLeu-OH CAS:89536-84-5

Boc-D-MeLeu-OH waxaa si ballaaran loogu isticmaalaa isku-darka peptide-ka marxaladda adag si loo abuuro peptides-yo gaar ah oo leh taxane iyo shaqooyin gaar ah. Iyada oo ah qaab la ilaaliyo oo ah DN-methyl-leucine, waxay u oggolaanaysaa in la xakameeyo soo bandhigidda haraaga DN-methyl-leucine silsiladda peptide-ka ee sii kordheysa, taasoo ka hortagaysa falcelinta dhinaca aan loo baahnayn iyo awood u siinta isku-darka peptides-ka adag oo leh sifooyin loo habeeyay. Bayoolajiga iyo bayoolajiga kiimikada, Boc-D-MeLeu-OH waxay u adeegtaa sidii baloog dhisme oo kala duwan oo loogu talagalay abuurista peptides-ka bioactive, baaritaannada calaamadaysan, iyo daaweynta ku salaysan peptide. Isticmaalkeedu wuxuu suurtogal ka dhigayaa wax ka beddelka saxda ah ee peptides-ka iyo borotiinnada, taasoo fududeyneysa horumarinta molecules-ka badan ee shaqeynaya iyadoo la xoojiyay xasilloonida, gaar ahaanta bartilmaameedka, ama awoodaha sawir-qaadista ee codsiyada kala duwan ee bayoolajiga. Intaa waxaa dheer, helitaanka daawada iyo horumarinta daaweynta, Boc-D-MeLeu-OH waxaa loo adeegsadaa in lagu abuuro isku-xidhka peptide iyo peptides-ka wax laga beddelay oo leh astaamo farmashiye-kinetic ah oo la wanaajiyey iyo hawlo bayooloji. Wax-ka-beddelkani wuxuu kor u qaadi karaa waxtarka, xulashada, iyo keenista daawooyinka ku salaysan peptide, taasoo gacan ka geysanaysa horumarinta daawada saxda ah iyo daaweynta la beegsanayo. Guud ahaan, isku halaynta iyo kala-duwanaanta Boc-D-MeLeu-OH ee isku-darka peptide iyo bioconjugation waxay ka dhigaysaa qalab lama huraan ah oo lagu horumarinayo cilmi-baarista ku saabsan helitaanka daawada, bayoolajiga kiimikada, iyo proteomics, iyadoo bixinaysa fursado kala duwan oo lagu horumarinayo codsiyada biomedical-ka ee cusub.