Acetylcholinesterase CAS:9000-81-1

Anticholinesterases waa nooc ka mid ah daawooyinka ama kiimikooyinka joojiya dhaqdhaqaaqa enzyme-ka acetylcholinesterase. Acetylcholinesterase ayaa mas'uul ka ah burburinta acetylcholine neurotransmitter-ka ee jirka ku jira. Iyagoo joojinaya ensaymkan, anticholinesterases waxay kordhiyaan heerarka acetylcholine, taasoo horseedaysa firfircooni cholinergic ah oo kordhaysa oo ku jirta habdhiska neerfaha dhexe iyo kan durugsan.

Isticmaalka ugu weyn ee daaweynta anticholinesterases waa daaweynta xanuunada neerfaha sida cudurka Alzheimers iyo myasthenia gravis. Cudurka Alzheimers, daawooyinkani waxay higsanayaan inay kor u qaadaan gudbinta neerfaha ee cholinergic waxayna suurtogal u tahay inay hoos u dhigaan hoos u dhaca garashada. Myasthenia gravis, anticholinesterases waxay gacan ka geystaan hagaajinta gudbinta murqaha iyo xoogga murqaha.

Isticmaalka kale ee anticholinesterases waxaa ka mid ah ogaanshaha iyo daaweynta sunta anticholinergic, gaar ahaan sunta cayayaanka ama wakiilada neerfaha qaarkood. Walxahani waxay sababi karaan kicinta xad-dhaafka ah ee soo-dhoweeyayaasha muscarinic iyo nicotinic, taasoo keenta calaamado sida daciifnimada murqaha, gariirka, iyo walbahaarka neefsashada. Anticholinesterases waxay dib u celin karaan saameyntan iyagoo kordhinaya heerarka acetylcholine iyo tartanka walxaha sunta ah.

Dalbo ama Codso Qiimayn

Faahfaahinta Badeecada

Calaamadaha Alaabta

Codsiga iyo Saamaynta

Saamaynta anticholinesterase waxay tilmaamaysaa awoodda daawooyinka qaarkood ama kiimikooyinka ay ku joojin karaan dhaqdhaqaaqa enzyme-ka acetylcholinesterase. Acetylcholinesterase ayaa mas'uul ka ah burburinta acetylcholine neurotransmitter-ka ee jirka ku jira. Iyagoo joojinaya ensaymkan, anticholinesterases waxay kordhiyaan heerarka acetylcholine, taasoo horseedaysa firfircooni cholinergic ah oo kordhay.

Isticmaalka ugu muhiimsan ee anticholinesterases waa daaweynta xaaladaha lagu garto hoos u dhaca dhaqdhaqaaqa cholinergic. Kuwaas waxaa ka mid ah xanuunnada neerfaha sida cudurka Alzheimers iyo myasthenia gravis. Cudurka Alzheimers, anticholinesterases sida donepezil, rivastigmine, iyo galantamine ayaa loo isticmaalaa in lagu joojiyo burburka acetylcholine iyo in la wanaajiyo gudbinta neerfaha ee cholinergic. Tani waxay gacan ka geysan kartaa hagaajinta shaqada garashada waxayna suurtogal u tahay inay hoos u dhigto horumarka cudurka.

Myasthenia gravis, anticholinesterases sida neostigmine iyo pyridostigmine ayaa loo isticmaalaa in lagu xoojiyo gudbinta neerfaha. Daawooyinkani waxay joojiyaan acetylcholinesterase waxayna kordhiyaan heerarka acetylcholine ee isgoyska neerfaha, iyagoo hagaajinaya xoogga murqaha iyo yareynta daciifnimada murqaha.

Anticholinesterases waxay sidoo kale leeyihiin adeegsiyo ogaansho iyo daaweyn ah oo loogu talagalay kiisaska sunta anticholinergic. Isku-darka anticholinergic, sida sunta cayayaanka qaarkood ama wakiilada neerfaha, waxay sababi karaan xannibaad xad dhaaf ah oo cholinergic ah taasoo keenta calaamado sida jahawareer, garaaca wadnaha oo degdeg ah, af qalalan, iyo aragti aan caddayn. Xaaladaha noocaas ah, anticholinesterases sida pralidoxime ayaa loo isticmaali karaa in lagu beddelo saamaynta iyadoo la kordhinayo heerarka acetylcholine iyo la tartanta walxaha sunta ah.

Baakaynta Alaabta:

Macluumaad Dheeraad ah:

Halabuurka	NA
Baaritaan	99%
Muuqaalka	Budada jaalaha ah ee khafiifka ah
Lambarka CAS.	9000-81-1
Baakad	Yar iyo weyn
Muddada Khafiska	2 sano
Kaydinta	Ku kaydi meel qabow oo qalalan
Shahaadada	ISO.