2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS:86520-63-0 Sawirka

2,3,4,6-Tetra-O-acetyl-a-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS:86520-63-0

2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate waa kiimiko kiimiko ah oo inta badan loo isticmaalo kiimikada karbohaydraytyada iyo falcelinta glycosylation.Waa nooc ka mid ah α-D-galactopyranose, nooc sonkor ah, halkaasoo kooxaha hydroxyl ee 2, 3, 4, iyo 6 ee giraanta galactopyranose ay yihiin acetylated.Intaa waxaa dheer, kaarboonka anomeric (C1) ee sonkorta waxaa lagu ilaaliyaa koox trichloroacetimidate, taas oo ka dhigaysa koronto xoog leh inta lagu jiro falcelinta glycosylation.

Xarunta waxaa badanaa loo isticmaalaa sida wakiilka glycosylating si loogu soo bandhigo unugyada galactose molecules kala duwan, sida borotiinada, peptides, ama molecules organic yar yar.Tan waxaa lagu gaari karaa iyadoo lagu falcelinayo xaruntan nucleophile (tusaale, kooxaha hydroxyl ee molecule bartilmaameedka ah) iyadoo lagu jiro xaalado ku habboon.Kooxda trichloroacetimidate waxay sahlaysa ku-xidhka unugyada galactose ee molecule bartilmaameedka, taasoo keentay samaynta curaarta glycosidic.

Xaruntan waxaa sida caadiga ah loo adeegsadaa isku dhafka glycoconjugates, glycopeptides, iyo glycolipids.Waxay bixisaa hab wax ku ool ah oo wax ku ool ah oo loogu talagalay in lagu beddelo molecules leh hadhaaga galactose, kuwaas oo ku habboonaan kara dhinacyo kala duwan, oo ay ku jiraan daraasadaha bayoolojiga, hababka bixinta daroogada, ama horumarinta tallaalka.

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Glycosylation: Xaruntu waxay la falgashaa unugyo kala duwan oo aqbalaad ah oo ay ku jiraan kooxaha hydroxyl, sida khamriga ama amines, si ay u sameeyaan curaarta glycosidic.Tani waxay u oggolaaneysaa soo-gelinta galactose-ka molecule-ka aqbalaha, taasoo keentay isku-dhafka glycoconjugates, glycopeptides, ama glycolipids.

Cilmi-baadhista bayoloji iyo kiimikaad: Iskudhisku waxa uu ka caawiyaa cilmi-baarayaasha in ay daraaseeyaan hawlaha bayooloji iyo isdhexgalka unugyada galactose-ka ku jira.Iyaga oo si xushmad leh ugu dhejinaya galactose borotiinada, peptides, ama biomolecules kale, cilmi-baarayaashu waxay baari karaan doorkooda hababka gacanta, isdhexgalka receptor-ligand, iyo hababka cudurada.

Nidaamyada gudbinta daroogada: Xarunta waxaa loo isticmaali karaa in lagu beddelo molecules daroogada leh hadhaaga galactose, fududaynta gaarsiinta daroogada la beegsaday unugyo gaar ah ama unugyo.Galactose wuxuu u dhaqmi karaa sidii ligand la beegsanayo, isagoo aqoonsanaya soo-dhoweeyayaal gaar ah oo lagu muujiyay dusha unugyada, gaar ahaan hepatocytes.Marka lagu dhejiyo galactose daroogooyinka, cilmi-baarayaashu waxay kor u qaadi karaan doorashadooda iyo waxtarkooda daaweynta la beegsaday.

Horumarinta tallaalka: Unugyada galactose-ka ku jira waxay door muhiim ah ka ciyaaraan jawaabaha difaaca jirka, maadaama ay aqoonsan yihiin lectins ku jira unugyada difaaca.Marka la isku daro antigens-yada galactose moieties iyadoo la isticmaalayo xaruntan, cilmi-baarayaashu waxay kor u qaadi karaan jawaabaha difaaca waxayna soo saari karaan tallaalo waxtar leh.

Isku-dubarid kiimikaad: Xarunta waxa loo adeegsan karaa isku-dubbarid kiimiko oo kala duwan halkaas oo wax-ka-beddelka galactose loo baahan yahay.Tan waxaa ka mid ah diyaarinta qaababka karbohaydrayt ee adag, oligosaccharides, ama glycomimetics, kuwaas oo si dheeraad ah loogu isticmaali karo kimistariga daawada ama aaladaha cilmi baarista.

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Xog dheeraad ah:

Halabuurka	C16H20Cl3NO10
Qiimayn	99%
Muuqashada	budo cad
CAS Maya.	86520-63-0
Baakad	Yar iyo weyn
Nolosha shelf	2 sano
Kaydinta	Ku kaydi meel qabow oo qalalan
Shahaado	ISO.