2,2,2-Trifluoroacetamid CAS:354-38-1

2,2,2-Trifluoroacetamide, oo sidoo kale loo yaqaan trifluoroacetamide, waa bir adag oo aan midab lahayn oo lagu garto ur fiiqan oo fiiqan. Iyada oo la adeegsanayo qaacidada kiimikada CF3CONH2, waxay door muhiim ah ka ciyaartaa kiimikada dabiiciga ah, iyadoo raadinaysa codsiyada warshadaha kala duwan. Astaamaha 2,2,2-Trifluoroacetamide waxay leedahay koox trifluoromethyl ah (-CF3) oo ku xiran laf-dhabarta acetamide. Qaab-dhismeedkan qaab-dhismeedka wuxuu saameeyaa sifooyinkiisa jireed iyo kiimikada. Waxay u jirtaa sidii bir adag oo aan midab lahayn, oo si yar ugu milmi karta biyaha laakiin si fudud ugu milmi karta dareerayaasha dabiiciga ah sida acetone iyo ether. Waxay leedahay dhibic dhalaalaysa oo ku dhow 72°C. Adeegsiga Kooxda Ilaalinta ee Isku-darka Peptide: Mid ka mid ah codsiyada aasaasiga ah ee 2,2,2-trifluoroacetamide waa koox ilaalin ah oo loogu talagalay amines-ka isku-darka peptide. Iyada oo xannibaysa kooxda shaqaynaysa ee amine, waxay ka hortagtaa falcelinta dhinaca aan loo baahnayn, taasoo u oggolaanaysa sameynta isku-xidhka peptide ee xulashada. Isku-darka Kiimikada: Isku-darka wuxuu u adeegaa sidii baloog dhisme oo kala duwan oo ku jira isku-darka dabiiciga ah. Waxaa loo isticmaalaa soo saarista daawooyinka, kiimikooyinka beeraha, iyo kiimikooyinka gaarka ah sababtoo ah fal-celinta kiimikada ee gaarka ah iyo xasilloonida. Dareeraha: Trifluoroacetamide waxaa loo isticmaalaa sidii dareere ah hababka kiimikada ee kala duwan, taasoo sahlaysa kala dirista iyo maaraynta walxaha codsiyada warshadaha ee kala duwan. Isku-darka 2,2,2-Trifluoroacetamide waxaa lagu samayn karaa dhowr hab. Hal hab oo caadi ah ayaa ku lug leh fal-celinta u dhaxaysa trifluoroacetic acid iyo ammonia, taasoo soo saarta trifluoroacetamide oo ay weheliso biyo ahaan wax soo saar. Fal-celinta waxaa badanaa lagu sameeyaa xaalado la xakameeyey si loo hubiyo daahirnimo iyo wax-soo-saar sare. Gunaanad ahaan, 2,2,2-trifluoroacetamide waa isku-dhafan badan oo si weyn loogu isticmaalo isku-darka dabiiciga ah, gaar ahaan kiimikada peptide. Sifooyinkeeda kala duwan iyo fal-celinta kiimikada ayaa ka dhigaya mid aan lagama maarmaan u ah warshadaha kala duwan, oo ay ku jiraan daawooyinka, kiimikooyinka beeraha, iyo kiimikooyinka gaarka ah, halkaas oo ay gacan ka geysato isku-darka alaabada kala duwan.