α-Galactosesidase CAS:9025-35-8

α-galactosidase(α-galactosidase, α-gal, EC 3.2.1.22) waa exoglycosidase kaas oo kiciya hydrolysis-ka xidhmooyinka α-galactosidic. Maadaama ay burburin karto melibiose, waxaa sidoo kale loo yaqaan melibiase, kaas oo kiciya hydrolysis-ka xidhmooyinka α-galactosidic. Sifadan waxay ka dhigaysaa mid waxtar u leh hagaajinta iyo baabi'inta qaybaha ka hortagga nafaqada ee cuntada quudinta iyo cuntooyinka ku salaysan soy. Intaa waxaa dheer, waxay xaqiijin kartaa beddelka nooca dhiigga B→O ee goobta caafimaadka, waxay diyaarin kartaa dhiigga guud, waxayna ka ciyaari kartaa door muhiim ah daaweynta beddelka ensaymka ee cudurka Fabry. α-galactosidase waxay sidoo kale ka shaqayn kartaa polysaccharides-ka adag, glycoproteins iyo glycosphingoses oo ka kooban xidhmooyinka α-galactosidic. Qaar ka mid ah α-galactosidases ayaa sidoo kale transgalactosylate kara marka fiirsashada substrate-ka si weyn loo kobciyo, astaantan waxaa loo isticmaali karaa isku-darka oligosaccharides iyo diyaarinta waxyaabaha ka soo baxa cyclodextrin. Horumarinta neutrophil ama pH-xasilloon α-galactosidase iyo raadinta noolaha yaryar ama dhirta leh wax soo saarka ensaymka sare ayaa noqday meelaha ugu badan ee cilmi-baarista sannadihii ugu dambeeyay. α-galactosidase badan oo u adkaysta kulaylka ayaa sidoo kale si tartiib tartiib ah u kiciyay xiisaha ballaaran ee saynisyahannada sababtoo ah gaar ahaanshahooda, iyagoo rajeynaya inay isticmaalaan xasilloonidooda kulaylka si ay u ciyaaraan qiimo weyn oo loo isticmaalo warshadaha, iyo inay muujiyaan codsiyo ballaaran oo ku saabsan dhinacyada tignoolajiyada, tignoolajiyada iyo daawada.