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N, N-Bis (2-hydroxyethyl) -2-aminoethanesulfonic acid sodium cusbo CAS: 66992-27-6
N, N-Bis (2-hydroxyethyl) -2-aminoethanesulfonic acid sodium cusbo, oo sidoo kale loo yaqaan HEPES sodium cusbo, waa iskudhis kiimiko oo caadi ahaan loo isticmaalo wakiilka pH ee shaybaarada noolaha iyo kiimikaad.Waxay ka caawisaa ilaalinta kala duwanaanta pH xasilloon, taas oo ka dhigaysa mid ku habboon codsiyada sida dhaqanka unugyada, imtixaannada enzymes, daraasadaha borotiinka, electrophoresis, iyo hababka daawooyinka.HEPES sodium cusbada waxay hubisaa xaaladaha ugu fiican ee hababka noolaha waxayna kor u qaadaysaa saxnaanta iyo isku halaynta natiijooyinka tijaabada.
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2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACIID SODIUM SALAT CAS:76204-02-9
2′-(4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium cusbada waa ka kooban kiimiko oo caadi ahaan loo isticmaalo baaritaanka ogaanshaha iyo cilmi-baarista.Waa nooc ka soo jeeda sialic acid, oo ah nooc ka mid ah unugyada karbohaydrayt ee laga helo dusha unugyada.
Xaruntan waxaa loo isticmaalaa sidii substrate loogu talagalay enzymes loo yaqaan neuraminidases, kuwaas oo u dhaqma inay ka saaraan sialic acid hadhaaga glycoproteins iyo glycolipids.Marka enzymes-ku ay u dhaqmaan 2'- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium sodium, waxay sii daysaa badeecada fluorescent ee loo yaqaan 4-methylumbelliferone.
Fluorescence-ka ay dhaliso xaruntu waa la qiyaasi karaa oo la qiyaasi karaa, iyadoo la siinayo macluumaadka ku saabsan waxqabadka enzymes neuraminidase.Tani waxay si gaar ah faa'iido u leedahay daraasadda cudurrada kala duwan iyo xaaladaha la xidhiidha dheef-shiid kiimikaad sialic acid ah.
Xarunta ayaa sidoo kale loo isticmaalaa ujeedooyinka ogaanshaha, sida ogaanshaha caabuqyada fayraska ee ku lug leh waxqabadka neuraminidase.Qiimayntan, xarunta waxaa loo isticmaalaa in lagu aqoonsado joogitaanka fayraska gaarka ah ama la qiimeeyo waxtarka neuraminidase inhibitors ee daaweynta fayraska.
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TAPSO CAS: 68399-81-5 Qiimaha soo saaraha
TAPSO (3-[N-tris(hydroxymethyl)methyl]amino]-2-hydroxypropanesulfonic acid) waa kaydka zwitterionic oo caadi ahaan loo isticmaalo cilmi-baarista bayooloji iyo kiimikaad.Waa wakiil wax-ku-ool ah oo leh pKa oo ku dhow pH jireed, taasoo ka dhigaysa mid ku habboon ilaalinta pH xasilloon ee tijaabooyinka noolaha.TAPSO waxaa inta badan loo adeegsadaa sifaynta borotiinka, imtixaannada enzymes-ka, dhaqanka unugga, iyo codsiyada electrophoresis.Biyo-millaynta sare ee biyaha iyo faragelinta hoose ee hababka bayoolojiga ayaa ka dhigaya doorashada caanka ah ee bulshada sayniska.TAPSO waxay caan ku tahay saamaynta ugu yar ee ay ku leedahay dhaqdhaqaaqa ensaymka waxaana badanaa loo isticmaalaa beddelka wakiilada kale ee kaydinta sida Tris ama fosfooraska.
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N-Acetyl-L-cysteine CAS:616-91-1
N-Acetyl-L-cysteine (NAC) waa nooc la beddelay oo ah cysteine-ka amino acid.Waxay bixisaa isha cysteine-ka waxaana si sahal ah loogu beddeli karaa glutathione tripeptide, oo ah antioxidant awood leh oo jirka ku jira.NAC waxay caan ku tahay sifooyinka antioxidant iyo mucolytic, taas oo ka dhigaysa mid faa'iido u leh codsiyada caafimaadka ee kala duwan.
Sida antioxidant-ka, NAC waxay ka caawisaa inay unugyada ka ilaaliso waxyeelada ay keenaan xagjirrada xorta ah, noocyada ogsijiinta falcelinta, iyo sunta.Waxa kale oo ay taageertaa isku-dhafka glutathione, kaas oo door muhiim ah ka ciyaara hababka sun-saarista jidhka iyo ilaalinta nidaamka difaaca caafimaadka leh.
NAC waxaa lagu bartay faa'iidooyinka ay ka heli karto caafimaadka neefsashada, gaar ahaan shakhsiyaadka qaba xaaladaha sida boronkiitada raaga, COPD, iyo cystic fibrosis.Caadi ahaan waxaa loo isticmaalaa sidii rasiiye si ay u caawiso dhuuban iyo dabacsanaanta xabka, taas oo sahlaysa in la nadiifiyo marinnada hawo-mareenka.
Intaa waxaa dheer, NAC waxay muujisay ballanqaad ku aaddan taageeridda caafimaadka beerka iyada oo gacan ka geysanaysa ka saarista walxaha sunta ah, sida acetaminophen, xanuunka fudud ee caadiga ah.Waxa kale oo laga yaabaa inay yeelato saamayn ka hortag ah dhaawaca beerka ee ay keento cabbidda khamriga.
Marka laga soo tago sifooyinka ay leedahay antioxidant-ka iyo taageerada neefsashada, NAC waxaa lagu sahamiyay faa'iidooyinka suurtagalka ah ee caafimaadka dhimirka.Cilmi-baadhisyada qaarkood waxay soo jeedinayaan in laga yaabo inay saameyn togan ku yeelato cilladaha niyadda, sida niyad-jabka iyo xanuunka waswaaska (OCD).
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TUBEES CAS: 5625-37-6 Qiimaha soo saaraha
PIPES (piperazine-1,4-bisethanesulfonic acid) waa iskudhis buffering zwitterionic caadi ahaan loo isticmaalo cilmi bayooloji iyo bayooloji.Waa kaydiye wax ku ool ah oo leh awood sare oo lagu ilaalinayo xaaladaha pH ee xasilloon ee kala duwan pH ee 6.1 ilaa 7.5.PIPES waxay leedahay faragelinta ugu yar ee biomolecules waxayna ku habboon tahay qiyaasaha heerkulka ku-tiirsanaanta.Badanaa waxaa loo adeegsadaa farsamooyinka jel electrophoresis iyo samaynta dawooyinka sida wakiilka xasilinta.Guud ahaan, PIPES waa isku-dhafan oo si ballaaran loo isticmaalo goobo tijaabo ah oo kala duwan.
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2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniuM-9-carboxylate 4′-NHS Ester CAS:194357-64-7
2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4′-NHS ester waa unug kiimiko oo leh qaab dhismeed unugyo isku dhafan.Waxay ka kooban tahay koox sulfopropylacridinium ah iyo koox shaqaynaysa ester-karboxilate.Joogitaanka unugyada ester-ka ayaa tilmaamaya in uu falceliyo oo loo isticmaali karo calaamad ahaan ama wax ka beddelka wakiilka biomolecules.
Kooxda sulfopropylacridinium ee xarunta waxay soo jeedinaysaa in laga yaabo inay lahaato codsiyo suurtagal ah oo ku saabsan tijaabooyinka fluorescence-ku-salaysan, halkaas oo loo isticmaali karo dheesha fluorescent ama dheeha loogu talagalay ogaanshaha iyo falanqaynta biomolecules.Waxa kale oo laga yaabaa inay ku habboonaato daraasadaha hababka gacanta, sida calaamadaynta calcium intracellular.
Ku darida kooxda ester-ka ee NHS waxay muujinaysaa inay ka falcelin karto aminyada aasaasiga ah, sida kuwa laga helo borotiinnada ama peptides, si loo sameeyo curaarta amide deggan.Dareen-celintani waxay faa'iido u leedahay codsiyada bioconjugation, halkaas oo loo isticmaali karo in lagu calaamadiyo ama lagu beddelo biomolecules kale oo shaqeynaya, sida fluorophores ama tags.
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5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide CAS:4264-82-8
5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide waa iskudhis loo isticmaalo daraasaadka biochemical ee kala duwan, gaar ahaan ogaanshaha iyo aragga ee hawlaha enzyme.Waa substrate-ka lagu nadiifin karo enzymes gaar ah, taasoo keentay in la sii daayo badeecad midab leh ama fluorescent ah.
Xaruntan waxaa caadi ahaan loo isticmaalaa baaritaannada si loo ogaado joogitaanka iyo dhaqdhaqaaqa enzymes sida beta-galactosidase iyo beta-glucuronidase.Enzymes-yadani waxay ka gooyaan kooxaha acetyl iyo glucosaminide substrate, taasoo horseedaysa samaynta koromophore buluug ama cagaar ah.
Qaab dhismeedka gaarka ah ee 5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide waxay u oggolaaneysaa in si sahlan loo ogaado iyo qiyaasidda dhaqdhaqaaqa enzyme.Isticmaalkeeda farsamooyin tijaabo ah oo kala duwan, oo ay ku jiraan histochemistry, immunohistochemistry, iyo imtixaannada unugyada ku salaysan, ayaa gacan ka geystay faham wanaagsan oo ku saabsan hawlaha enzyme.
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Sodium Salt Salt CAS: 139-41-3 Qiimaha soo saaraha
N, N-Bis (2-hydroxyethyl) glycine sodium cusbo waa iskudhis kiimiko ah oo loo isticmaalo sidii wakiilka kaydinta ee codsiyada kala duwan ee biochemical iyo biophysical.Waxay ka caawisaa ilaalinta heerka pH ee xaaladaha tijaabada ah, taas oo ka dhigaysa mid faa'iido u leh daraasadaha enzymes, cilmi-baarista borotiinka, dhaqanka unugyada, iyo farsamooyinka xoqidda galbeedka.
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Spinosad CAS: 131929-60-7 Soo saaraha Soo saaraha
Spinosad waa koox 5 nicotinic acetylcholine reseptor agonist, taas oo keenta murqaha aan ikhtiyaarka lahayn iyo gariirka labaad ee firfircoonida neerfaha.Soo-gaadhista daba-dheeraatay waxay keentaa curyaan iyo dhimasho dhinta.Dhimashada boodhku waxay ku bilaabataa 30 daqiiqo gudahooda ka dib marka la qaato 4 saacadood gudahooda way dhammaatay.Spinosad ma la fal gasho meelaha lagu xidho ee sunta cayayaanka kale (GABA-ergic ama nicotinic).
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Rotenone CAS: 83-79-4 Soo saaraha Soo saaraha
Rotenone waa labadaba caloosha iyo sunta taabasho ee arthropods.Ficilkeeda degdega ah ee garaacista waxaa loo aaneynayaa hoos u dhigista helitaanka nicotinamide adenine dinucleotide si ay ugu adeegto sidii isku-xidhaha dariiqyada biochemical ee kala duwan oo ay ku jiraan wareegga Krebs, taas oo joojinaysa enzymes neefsiga mitochondrial.
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Diazinon CAS: 333-41-5 Soo saaraha Soo saaraha
Diazinon waxaa lagu heli karaa qaab dareere maariin ah oo aan midab lahayn ama madow.Aad bay ugu milmi kartaa biyaha laakiin aad bay ugu milmi kartaa ether petroleum, alkohol, iyo benzene.Diazinon waxaa loo isticmaalaa xakamaynta beeraha kala duwan iyo cayayaanka guryaha.Kuwaas waxaa ka mid ah cayayaanka ku jira ciidda, dhirta qurxinta, khudradda, khudradda, iyo dalagyada iyo cayayaanka guriga sida duqsigu, boodada, iyo baranbaro.
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Avermectin CAS: 71751-41-2 Soo saaraha Soo saaraha
Abamectin (Avermectin) waa walax sun ah neerfaha.Nidaamkeedu wuxuu bartilmaameedsanayaa soo-dhoweeyaha GABAA ee cayayaanka neuron synapse ama neuromuscular synapse, oo farageliya wareejinta macluumaadka ee xididada dareemayaasha, kuwaas oo kicinaya dareemayaasha dareemayaasha si ay u sii daayaan neurotransmitter γ-aminobutyric acid (GA-BA), taasoo keentay furitaanka ballaaran ee GABA-gated chloride channel oo leh saamayn firfircoonida kanaalka koloridhida.
