Itraconazole CAS: 84625-61-6 Soo saaraha Soo saaraha

Itraconazole waa clotrimazole synthetic si dabiici ah, isagoo ah wakiilka antifungal synthetic ballaaran.Xakameynteeda antimicrobial spectrum iyo habka ka hortagga jeermiska bakteeriyada waxay la mid tahay clotrimazole, laakiin waxay leedahay firfircooni bakteeriyada lidka ku ah Aspergillus.Waxay ku shaqeysaa saameynteeda fangas-ka-soo-baxa iyada oo beddelaysa qulqulka xuubabka unugga fangas oo leh firfircoonida bakteeriyada lidka ku ah cudurada fangas ee dusha sare iyo qoto dheer.Bakteeriyadeeda bakteeriyada ayaa ka ballaadhan oo ka xoog badan ketoconazole, iyada oo awood u leh in ay joojiso isku-darka ergosterol ee xuubka unugyada fangas, sidaas darteed ciyaarta saamaynta antifungal.

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Itraconazole waa wakiilka antifungal triazole.Waxaa loo isticmaalaa in lagu joojiyo cytochrome P-450-ku-tiirsanaanta enzymes iyo ergosterol synthesis.Waxaa loo isticmaalay ka hortagga histoplasmosis, blastomycosis, cryptococcal meningitis, iyo aspergillosis.Waa qaabab kala duwan ayaa loo isticmaalaa in lagu barto noocyada Candida ee caabuqyada soo gala murine.Waxaa loo isticmaalay in lagu barto isbeddelada fidinta ee xuubka forestomach ee jiirka macaanka ee alloxan-induced.