Saldhigga Hydrocortisone CAS: 50-23-7 Soo saaraha Soo saaraha

Hydrocortisone, 11β,17,21-trihydroxypregn-4-ene-3,20-dione, waa bini'aadamka GCin aasaasiga ah ee dabiiciga ah.In kasta oo tirada badan ee GCs-synthetic, hydrocortisone, esters-keeda, iyo milixdeedu ay weli yihiin tiir-dhexaadka daaweynta steroid adrenocortical casriga ah iyo heerka isbarbardhigga dhammaan GC-yada kale iyo MC-yada.Waxaa loo adeegsaday dhammaan calaamadihii hore loo sheegay.

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Codsiga iyo Saamaynta

Hydrocortisone waa endogenous, waxayna leedahay labadaba glucocorticoid iyo firfircoonida mineralocorticoid.Waa qaab-dhismeedka aasaasiga ah ee hawlaha glucocorticoid iyo mineralocorticoid ee dhammaan corticosteroids kale ayaa lagu xukumay.Cortisol waxa la sii daayaa iyada oo ka jawaabaysa walaaca iyo heerka hoose ee glucocorticoids ee dhiigga.Shaqadeeda aasaasiga ah waa in la kordhiyo sonkorta dhiigga iyada oo loo marayo gluconeogenesis;xakameynaya habka difaaca jirka;iyo kaalmaynta dufanka, borotiinka iyo dheef-shiid kiimikaadka karbohaydraytyada.