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2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACIID SODIUM SALAT CAS:76204-02-9

2′-(4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium cusbada waa ka kooban kiimiko oo caadi ahaan loo isticmaalo baaritaanka ogaanshaha iyo cilmi-baarista.Waa nooc ka soo jeeda sialic acid, oo ah nooc ka mid ah unugyada karbohaydrayt ee laga helo dusha unugyada.

Xaruntan waxaa loo isticmaalaa sidii substrate loogu talagalay enzymes loo yaqaan neuraminidases, kuwaas oo u dhaqma inay ka saaraan sialic acid hadhaaga glycoproteins iyo glycolipids.Marka enzymes-ku ay u dhaqmaan 2'- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium sodium, waxay sii daysaa badeecada fluorescent ee loo yaqaan 4-methylumbelliferone.

Fluorescence-ka ay dhaliso xaruntu waa la qiyaasi karaa oo la qiyaasi karaa, iyadoo la siinayo macluumaadka ku saabsan waxqabadka enzymes neuraminidase.Tani waxay si gaar ah faa'iido u leedahay daraasadda cudurrada kala duwan iyo xaaladaha la xidhiidha dheef-shiid kiimikaad sialic acid ah.

Xarunta ayaa sidoo kale loo isticmaalaa ujeedooyinka ogaanshaha, sida ogaanshaha caabuqyada fayraska ee ku lug leh waxqabadka neuraminidase.Qiimayntan, xarunta waxaa loo isticmaalaa in lagu aqoonsado joogitaanka fayraska gaarka ah ama la qiimeeyo waxtarka neuraminidase inhibitors ee daaweynta fayraska.


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Codsiga iyo Saamaynta

Baaritaanka Waxqabadka Neuraminidase: Xaruntan waxaa badanaa loo isticmaalaa in lagu cabbiro waxqabadka enzymes neuraminidase ee shaybaarada noolaha.Iyadoo la kormeerayo qulqulka soo baxa, cilmi-baarayaashu waxay go'aamin karaan heerka dhaqdhaqaaqa neuraminidase, kaas oo ka caawin kara daraasadda cudurrada iyo xaaladaha kala duwan.

Ogaanshaha Caabuqa Fayraska: Caabuqyo badan oo fayras ah, oo uu ku jiro hargabku, waxay ku lug leeyihiin waxqabadka neuraminidase.Xaruntan waxaa loo isticmaali karaa in lagu ogaado oo lagu qiyaaso joogitaanka noocyada fayraska gaarka ah iyadoo la cabbirayo dhaqdhaqaaqa fluorescent.Waxay si gaar ah faa'iido u leedahay qiimeynta waxtarka neuraminidase inhibitors ee daaweynta fayraska.

Falanqaynta Glycosylation: Sialic acid waa qayb muhiim ah oo ka mid ah glycoproteins iyo glycolipids.Iyadoo lagu darayo 2'- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium cusbada tijaabooyinka, cilmi-baarayaashu waxay heli karaan fikrado ku saabsan dheef-shiid kiimikaadka sialic acid, qaababka glycosylation, iyo hababka jireed ee la xidhiidha.

Helitaanka Dawada: Neuraminidase inhibitors waa nooc dawooyin ah oo loo isticmaalo daawaynta caabuqyada fayraska.Xaruntan waxaa loo isticmaali karaa daraasadaha daahfurka daroogada, caawinta cilmi-baarayaasha inay aqoonsadaan oo ay qiimeeyaan horjoogayaasha suurtagalka ah ee dhaqdhaqaaqa neuraminidase.

 

Xiritaanka alaabta:

6892-68-8-3

Xog dheeraad ah:

Halabuurka C21H26NNAO11
Qiimayn 99%
Muuqashada budo cad
CAS Maya. 76204-02-9
Baakad Yar iyo weyn
Nolosha shelf 2 sano
Kaydinta Ku kaydi meel qabow oo qalalan
Shahaado ISO.

 


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